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Galia Maik-Rachline

Explore the profile of Galia Maik-Rachline including associated specialties, affiliations and a list of published articles. Areas
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Citations 569
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Recent Articles
1.
Nadel G, Yao Z, Hacohen-Lev-Ran A, Wainstein E, Maik-Rachline G, Ziv T, et al.
Cell Commun Signal . 2024 Feb; 22(1):154. PMID: 38419089
Background: Although GqPCR activation often leads to cell survival by activating the PI3K/AKT pathway, it was previously shown that in several cell types AKT activity is reduced and leads to...
2.
Nadel G, Maik-Rachline G, Seger R
Int J Mol Sci . 2023 Sep; 24(17). PMID: 37686335
The response of cells to extracellular signals is mediated by a variety of intracellular signaling pathways that determine stimulus-dependent cell fates. One such pathway is the cJun-N-terminal Kinase (JNK) cascade,...
3.
Wainstein E, Maik-Rachline G, Blenis J, Seger R
Cell Rep . 2022 Dec; 41(10):111733. PMID: 36476861
AKT is a central signaling protein kinase that plays a role in the regulation of cellular survival metabolism and cell growth, as well as in pathologies such as diabetes and...
4.
Wortzel I, Porat Z, Seger R, Maik-Rachline G
STAR Protoc . 2022 Apr; 3(2):101278. PMID: 35403004
The Golgi apparatus is subjected to fragmentation under several cellular processes such as mitosis. Here we describe two complementary approaches to analyze different Golgi morphological changes during its mitotic fragmentation,...
5.
Nadel G, Yao Z, Wainstein E, Cohen I, Ben-Ami I, Schajnovitz A, et al.
Cell Commun Signal . 2022 Jan; 20(1):5. PMID: 34998390
Background: G protein-coupled receptors (GPCRs) usually regulate cellular processes via activation of intracellular signaling pathways. However, we have previously shown that in several cell lines, GqPCRs induce immediate inactivation of...
6.
Maik-Rachline G, Wortzel I, Seger R
Cells . 2021 Dec; 10(12). PMID: 34943973
The mitogen-activated protein kinase (MAPK) cascades transmit signals from extracellular stimuli to a variety of distinct cellular processes. The MAPKKs in each cascade specifically phosphorylate and activate their cognate MAPKs,...
7.
Wortzel I, Maik-Rachline G, Yadav S, Hanoch T, Seger R
iScience . 2021 Jun; 24(6):102670. PMID: 34189435
ERK1c is an alternatively spliced isoform of ERK1 that specifically regulates mitotic Golgi fragmentation, which allows division of the Golgi during mitosis. We have previously shown that ERK1c translocates to...
8.
Maik-Rachline G, Lifshits L, Seger R
Int J Mol Sci . 2020 Aug; 21(17). PMID: 32847129
The p38 mitogen-activated protein kinase (p38MAPK, termed here p38) cascade is a central signaling pathway that transmits stress and other signals to various intracellular targets in the cytoplasm and nucleus....
9.
Arafeh R, Flores K, Keren-Paz A, Maik-Rachline G, Gutkind N, Rosenberg S, et al.
Sci Rep . 2019 Mar; 9(1):4672. PMID: 30858388
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
10.
Maik-Rachline G, Hacohen-Lev-Ran A, Seger R
Int J Mol Sci . 2019 Mar; 20(5). PMID: 30857244
The extracellular signal-regulated kinases 1/2 (ERK) are central signaling components that regulate stimulated cellular processes such as proliferation and differentiation. When dysregulated, these kinases participate in the induction and maintenance...