Guy Lippens
Overview
Explore the profile of Guy Lippens including associated specialties, affiliations and a list of published articles.
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Articles
137
Citations
2762
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Recent Articles
1.
Leprevost L, Junger S, Lippens G, Guillaume C, Sicoli G, Oliveira L, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(49):e2408304121.
PMID: 39602266
Ribosomally synthesized and posttranslationally modified peptides (RiPPs) are a structurally diverse group of natural products that bacteria employ in their survival strategies. Herein, we characterized the structure, the biosynthetic pathway,...
2.
Ammar Khodja L, Campanacci V, Lippens G, Gigant B
PNAS Nexus
. 2024 Nov;
3(11):pgae487.
PMID: 39534653
Tau is a protein involved in the regulation of axonal microtubules in neurons. In pathological conditions, it forms filamentous aggregates which are molecular markers of neurodegenerative diseases known as tauopathies....
3.
Li X, Lippens G, Parrou J, Cioci G, Esque J, Wang Z, et al.
mSphere
. 2024 Jul;
9(8):e0027824.
PMID: 39012103
In ruminants, the rumen is a specialized stomach that is adapted to the breakdown of plant-derived complex polysaccharides through the coordinated activities of a diverse microbial community. Bacteroidota is a...
4.
Charlier C, Gavalda S, Grga J, Perrot L, Gabrielli V, Lohr F, et al.
Biophys J
. 2024 Apr;
123(12):1542-1552.
PMID: 38664965
Enzymatic recycling of plastic and especially of polyethylene terephthalate (PET) has shown great potential to reduce its negative impact on our society. PET hydrolases (PETases) have been optimized using rational...
5.
Charlier C, Cox N, Prudhomme S, Geffard A, Nuzillard J, Luy B, et al.
Magn Reson (Gott)
. 2023 Oct;
2(2):619-627.
PMID: 37905230
The heteronuclear single quantum correlation (HSQC) experiment developed by Bodenhausen and Ruben (1980) in the early days of modern nuclear magnetic resonance (NMR) is without a doubt one of the...
6.
Murray A, Yan L, Gibson J, Liu J, Eliezer D, Lippens G, et al.
Biomolecules
. 2022 Nov;
12(11).
PMID: 36358923
(1) Background: Prion-like transcellular spreading of tau pathology in Alzheimer's disease (AD) is mediated by tau binding to the cell-surface glycan heparan sulfate (HS). However, the structural determinants for tau-HS...
7.
Morel J, Mokrzycki N, Lippens G, Drobecq H, Sautiere P, Hugues M
Toxins (Basel)
. 2022 Nov;
14(11).
PMID: 36356031
The pharmacology of calcium-activated chloride current is not well developed. Peptides from scorpion venom present potent pharmacological actions on ionic conductance used to characterize the function of channels but can...
8.
Tauzin A, Wang Z, Cioci G, Li X, Labourel A, Machado B, et al.
mSphere
. 2022 Aug;
7(5):e0024422.
PMID: 36043703
In the human gut microbiota, break down dietary and endogenous glycosides through highly specific polysaccharide utilization loci (PULs). PULs encode a variety of sensor regulators, binding proteins, transporters, and carbohydrate-active...
9.
Charlier C, Gavalda S, Borsenberger V, Duquesne S, Marty A, Tournier V, et al.
Biophys J
. 2022 Jul;
121(15):2882-2894.
PMID: 35794828
Plastic environmental pollution is a major issue that our generation must face to protect our planet. Plastic recycling has the potential not only to reduce the pollution but also to...
10.
Cox N, Charlier C, Vijayaraj R, De La Mare M, Barbe S, Andre I, et al.
Biochem Biophys Res Commun
. 2021 Dec;
589:223-228.
PMID: 34929445
Covalent protein complexes have been used to assemble enzymes in large scaffolds for biotechnology purposes. Although the catalytic mechanism of the covalent linking of such proteins is well known, the...