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Guus A M Kortman

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Recent Articles
11.
Leung T, Ulfman L, Chong M, Hon K, Khouw I, Chan P, et al.
Pediatr Allergy Immunol . 2020 May; 31(7):745-754. PMID: 32426882
Background: Bioactive proteins and human milk oligosaccharides (HMOs), important ingredients in breast milk, that protect against infections are lacking in young child formula (YCF). This study investigated the effects of...
12.
Paganini D, Uyoga M, Kortman G, Boekhorst J, Schneeberger S, Karanja S, et al.
Nutrients . 2019 Nov; 11(11). PMID: 31671757
There is little data on human milk oligosaccharide (HMO) composition in Sub-Saharan Africa. Iron fortificants adversely affect the infant gut microbiota, while co-provision of prebiotic galacto-oligosaccharides (GOS) mitigates most of...
13.
Gommers L, Ederveen T, van der Wijst J, Overmars-Bos C, Kortman G, Boekhorst J, et al.
FASEB J . 2019 Jul; 33(10):11235-11246. PMID: 31299175
Proton pump inhibitors (PPIs) are used by millions of patients for the treatment of stomach acid-reflux diseases. Although PPIs are generally considered safe, about 13% of the users develop hypomagnesemia....
14.
Paganini D, Uyoga M, Kortman G, Cercamondi C, Winkler H, Boekhorst J, et al.
Gut . 2018 Nov; 68(4):645-653. PMID: 30448776
Objective: Many African infants receiving iron fortificants also receive antibiotics. Antibiotic efficacy against enteropathogens may be modified by high colonic iron concentrations. In this study, we evaluated the effect of...
15.
Couto Furtado Albuquerque M, van Herwaarden Y, Kortman G, Dutilh B, Bisseling T, Boleij A
J Clin Pathol . 2017 Aug; 70(11):994-996. PMID: 28830908
No abstract available.
16.
Timmerman H, Rutten N, Boekhorst J, Saulnier D, Kortman G, Contractor N, et al.
Sci Rep . 2017 Aug; 7(1):8327. PMID: 28827640
The establishment of the infant gut microbiota is a highly dynamic process dependent on extrinsic and intrinsic factors. We characterized the faecal microbiota of 4 breastfed infants and 4 formula-fed...
17.
Paganini D, Uyoga M, Kortman G, Cercamondi C, Moretti D, Barth-Jaeggi T, et al.
Gut . 2017 Aug; 66(11):1956-1967. PMID: 28774885
Objective: Iron-containing micronutrient powders (MNPs) reduce anaemia in African infants, but the current high iron dose (12.5 mg/day) may decrease gut and , and increase enteropathogens, diarrhoea and respiratory tract...
18.
Kortman G, Reijnders D, Swinkels D
Hemodial Int . 2017 Mar; 21 Suppl 1:S28-S36. PMID: 28328083
Patients with chronic kidney disease (CKD) and loss of kidney function are at increased risk for morbidity and mortality. The risks of CKD are attributed to "uremia," an increased concentration...
19.
Kortman G, Dutilh B, Maathuis A, Engelke U, Boekhorst J, Keegan K, et al.
Front Microbiol . 2016 Jan; 6:1481. PMID: 26779139
Oral iron administration in African children can increase the risk for infections. However, it remains unclear to what extent supplementary iron affects the intestinal microbiome. We here explored the impact...
20.
Kortman G, Mulder M, Richters T, Shanmugam N, Trebicka E, Boekhorst J, et al.
Eur J Immunol . 2015 Jun; 45(9):2553-67. PMID: 26046550
Orally administrated iron is suspected to increase susceptibility to enteric infections among children in infection endemic regions. Here we investigated the effect of dietary iron on the pathology and local...