Guping Tang
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Explore the profile of Guping Tang including associated specialties, affiliations and a list of published articles.
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101
Citations
1118
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Recent Articles
1.
Lou Y, Dai C, Feng S, Jin R, Liu S, Zhou Z, et al.
Adv Mater
. 2025 Feb;
:e2417980.
PMID: 39988836
Wound healing remains a significant global health challenge, affecting millions annually and imposing substantial economic burdens. Most commercially available biomaterials for wound management primarily address external symptoms, including hemostasis, exudation,...
2.
Xu G, Tang G, Bai H
Angew Chem Int Ed Engl
. 2025 Feb;
:e202501058.
PMID: 39979214
Strict criteria of biomedical materials in synthesis efficiency, structure determinacy, and biological safety pose formidable challenges for the synthesis of dobby polypeptides. Herein we reported a cyclodextrin (CD)-initiated, 1,1,3,3-Tetramethylguanidine (TMG)-catalyzed...
3.
Wang Y, Zhou Q, Luo W, Yang X, Zhang J, Lou Y, et al.
J Nanobiotechnology
. 2024 Nov;
22(1):689.
PMID: 39523309
Pancreatic ductal adenocarcinoma (PDAC), characterized by a dense extracellular matrix (ECM), presents significant therapeutic challenges due to its poor prognosis and high resistance to chemotherapy. Current chemodrugs and diagnostic agents...
4.
Hou J, Bao H, Wang Y, Zhou Q, Chen J, Pan G, et al.
Small
. 2024 Oct;
21(1):e2407555.
PMID: 39468865
Altered redox homeostasis has long been observed in cancer cells, which can be exploited for therapeutic benefits. However, reactive oxygen species (ROS) pleiotropy coupling with reductive adaptation in cancer cells...
5.
Yu K, Wang Y, Sun H, Lou Y, Bao H, Wang X, et al.
ACS Appl Mater Interfaces
. 2024 Oct;
16(44):60070-60083.
PMID: 39436973
Multitarget tyrosine kinase inhibitors (TKIs) serve as first-line therapeutics in the systemic treatment of hepatocellular carcinoma (HCC), yet their clinical effectiveness is hampered by suboptimal pharmacokinetics and bioavailability. There is...
6.
He Y, Sun H, Bao H, Hou J, Zhou Q, Wu F, et al.
Biomaterials
. 2024 Aug;
312:122751.
PMID: 39121726
Tumor immunotherapies have emerged as a promising frontier in the realm of cancer treatment. However, challenges persist in achieving localized, durable immunostimulation while counteracting the tumor's immunosuppressive environment. Here, we...
7.
Zhang J, Yang X, Chen J, Zhou Q, Pan G, Wang Y, et al.
Nano Lett
. 2024 Jun;
24(27):8351-8360.
PMID: 38916238
Targeting telomere maintenance has emerged as a promising strategy for hepatocellular carcinoma (HCC) treatment. However, given the duality of the telomere-telomerase axis in telomere maintenance, a comprehensive strategy is urgently...
8.
Xue W, Lin X, Xu L, Trital A, He Y, Tang G, et al.
Adv Mater
. 2023 Aug;
35(49):e2304594.
PMID: 37651555
The quick diffusion of nanomedicines in the polysaccharide-gel-filling tumor interstitium and precise active targeting are two major obstacles that have not yet been overcome. Here, a poly(L-glutamyl-L-lysine(EK) (p(EK))-camouflaged, doxorubicin (Dox)-conjugated...
9.
Wang Y, Zhang H, Wang J, Tang G, Bai H
Mol Pharm
. 2023 Feb;
20(4):2128-2137.
PMID: 36848620
To overcome the hypoxia barrier in tumor therapy, a hypoxia-activated prodrug of docetaxel (DTX-PNB) was synthesized and self-assembled with indocyanine green (ICG), forming a combination nanomedicine ISDNN. With the guidance...
10.
Hu Q, Xu M, Feng J, Xie H, Li J, He Y, et al.
Nanoscale
. 2022 Oct;
14(42):15735-15748.
PMID: 36205175
For pancreatic ductal adenocarcinoma (PDAC) treatment, the deactivation of pancreatic stellate cells (PSCs) by blocking the transforming growth factor β (TGF-β) pathway is a promising strategy to inhibit stroma, enhance...