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Guping Tang

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Recent Articles
11.
Fan X, Xia Q, Liu S, Zheng Z, Zhang Y, Wu T, et al.
Mater Today Bio . 2022 Sep; 16:100399. PMID: 36052153
Fluorescence imaging-guided surgery is one of important techniques to realize precision surgery. Although second near-infrared window (NIR-II) fluorescence imaging has the advantages of high resolution and large penetration depth in...
12.
Chi X, Yu G, Ji X, Li Y, Tang G, Huang F
ACS Macro Lett . 2022 May; 4(9):996-999. PMID: 35596434
Here we report a redox-responsive host-guest complex between a new water-soluble pillar[5]arene () and a paraquat derivative. Compared with the neutral form of the paraquat derivative that binds weakly, its...
13.
Shen J, Wang Q, Fang J, Shen W, Wu D, Tang G, et al.
RSC Adv . 2022 May; 9(64):37232-37240. PMID: 35542287
To obtain an efficient dual-drug release and enhance therapeutic efficiency for combination chemotherapy, a glutathione (GSH)-responsive therapeutic amphiphilic polyprodrug copolymer (mPEG--PCPT) is synthesized to load doxorubicin (DOX) hydrophobic and π-π...
14.
Zhang M, Zhang W, Tang G, Wang H, Wu M, Yu W, et al.
ACS Appl Bio Mater . 2022 Jan; 2(3):1168-1176. PMID: 35021365
As the fourth leading cause of cancer-related deaths worldwide, pancreatic cancer has a higher basal level of autophagy as compared to other epithelial tumors. Recently, increasing evidence suggested that docetaxel...
15.
Liu X, Wu M, Wang M, Duan Y, Phan C, Qi G, et al.
Mater Horiz . 2021 Nov; 8(5):1454-1460. PMID: 34846453
A living therapeutic system based on attenuated Salmonella was developed via metabolic engineering using an aggregation-induced emission (AIE) photosensitizer MA. The engineered bacteria could localize in the tumor tissues and...
16.
Huang G, Chen Q, Hu J, Mao J, He Y, Bai H, et al.
Biomater Sci . 2021 Nov; 9(22):7412-7419. PMID: 34751282
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) treated patients ultimately develop disease progression, about 50% of which are involved in the emergence of a p.Thr790Met (T790M) mutation acquiring drug...
17.
Lou Y, Yu K, Wu X, Wang Z, Cui Y, Bao H, et al.
Molecules . 2021 Sep; 26(18). PMID: 34577193
Resveratrol (RSV) and polydatin (PD) have been widely used to treat several chronic diseases, such as atherosclerosis, pulmonary fibrosis, and diabetes, among several others. However, their low solubility hinders their...
18.
Wang P, Wang J, Zhang W, Bai H, Tang G, Young D
Chem Asian J . 2021 Aug; 16(19):2993-3000. PMID: 34387027
Nanoformulations of mononuclear Pt complexes cis-PtCl (PPh ) (1), [Pt(PPh ) (L-Cys)] ⋅ H O (3, L-Cys=L-cysteinate), trans-PtCl (PPh PhNMe ) (4; PPh PhNMe =4-(dimethylamine)triphenylphosphine), trans-PtI (PPh PhNMe ) (5)...
19.
Phan C, Shen J, Yu K, Liu J, Tang G
Int J Mol Sci . 2021 Jul; 22(13). PMID: 34206574
Sorafenib (Sor) is an oral multi-kinase inhibitor, but its water solubility is very low. To improve its solubility, sorafenib hydrochloride hydrate, sorafenib hydrobromide and sorafenib hydrobromide hydrate were prepared in...
20.
Phan C, Shen J, Yu K, Mao J, Tang G
Molecules . 2021 Jul; 26(11). PMID: 34200376
The dissolution rate is the rate-limiting step for Biopharmaceutics Classification System (BCS) class II drugs to enhance their in vivo pharmacokinetic behaviors. There are some factors affecting the dissolution rate,...