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Guoqiang Hua

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Articles 66
Citations 2559
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Recent Articles
21.
Seitlinger J, Nounsi A, Idoux-Gillet Y, Santos Pujol E, Le H, Grandgirard E, et al.
Biomedicines . 2022 May; 10(5). PMID: 35625840
Patient-derived tumoroid (PDT) has been developed and used for anti-drug screening in the last decade. As compared to other existing drug screening models, a PDT-based in vitro 3D cell culture...
22.
Li X, Fu G, Zhang L, Guan R, Tang P, Zhang J, et al.
Stem Cell Res Ther . 2022 May; 13(1):219. PMID: 35619149
Background: Organoids are three-dimensional structures that closely recapitulate tissue architecture and cellular composition, thereby holding great promise for organoid-based drug screening. Although growing in three-dimensional provides the possibility for organoids...
23.
Klingler S, Hsu K, Hua G, Martin M, Adileh M, Baslan T, et al.
JCI Insight . 2022 Mar; 7(5). PMID: 35260534
Recent data establish a logarithmic expansion of leucine rich repeat containing G protein coupled receptor 5-positive (Lgr5+) colonic epithelial stem cells (CESCs) in human colorectal cancer (CRC). Complementary studies using...
24.
Huang H, Chen S, Cheng H, Cao J, Du W, Zhang J, et al.
J Nanobiotechnology . 2022 Feb; 20(1):95. PMID: 35209908
Background: The promising therapeutic strategy for the treatment of peripheral artery disease (PAD) is to restore blood supply and promote regeneration of skeletal muscle regeneration. Increasing evidence revealed that prostaglandin...
25.
Bornert F, Clauss F, Hua G, Idoux-Gillet Y, Keller L, Fernandez De Grado G, et al.
Biomedicines . 2021 Aug; 9(8). PMID: 34440156
One major limitation for the vascularization of bone substitutes used for filling is the presence of mineral blocks. The newly-formed blood vessels are stopped or have to circumvent the mineral...
26.
Rao X, Tang P, Li Y, Fu G, Chen S, Xu X, et al.
Int J Radiat Oncol Biol Phys . 2021 Feb; 110(4):1210-1221. PMID: 33545304
Purpose: Radiation-induced gastrointestinal syndrome (RIGS) is currently the main cause of death for people exposed to a high dose of irradiation during nuclear incidents, and there is currently no approved...
27.
Li Y, Rao X, Tang P, Chen S, Guo Q, Fu G, et al.
Stem Cell Reports . 2020 Dec; 16(1):120-133. PMID: 33382975
Epithelial regeneration is critical for barrier maintenance and organ function after intestinal injury, although the repair mechanisms are unclear. Here, we found that Bach2 deficiency promotes intestinal epithelial cell proliferation...
28.
Zhang L, Mo S, Hu X, Ma X, Jin W, Peng D, et al.
Clin Transl Med . 2020 Dec; 10(8):e247. PMID: 33377635
No abstract available.
29.
Fu G, Chen S, Liang L, Li X, Tang P, Rao X, et al.
Cancer Lett . 2020 Dec; 501:20-30. PMID: 33359449
High-dose radiation exposure induces gastrointestinal (GI) stem cell death, resulting in denudation of the intestinal mucosa and lethality from GI syndrome, for which there is currently no effective therapy. Studying...
30.
Zhang R, He Y, Yao L, Chen J, Zhu S, Rao X, et al.
Environ Int . 2020 Nov; 146:106244. PMID: 33157379
Metformin (MET), a worldwide used drug for type 2 diabetes, has been found with the largest amount by weight among all drugs in aquatic environment, including the drinking water systems...