Guokai Pan
Overview
Explore the profile of Guokai Pan including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
269
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Recent Articles
1.
Guo L, Hong T, Lee Y, Hu X, Pan G, Zhao R, et al.
Nat Cell Biol
. 2024 Sep;
26(12):2154-2167.
PMID: 39251719
The ten-eleven translocation (TET) family of dioxygenases maintain stable local DNA demethylation during cell division and lineage specification. As the major catalytic product of TET enzymes, 5-hydroxymethylcytosine is selectively enriched...
2.
Li B, Xie S, Pan G, Lin Z, Ren S, Chen S, et al.
Oral Dis
. 2022 Sep;
30(2):140-148.
PMID: 36135340
Objectives: Accumulating studies have proved that the circular RNAs (circRNAs) play vital roles in human cancers. However, few circRNAs have been elucidated with lymph node metastasis. This study demonstrated that...
3.
Lei X, Lin H, Wang J, Ou Z, Ruan Y, Sadagopan A, et al.
Nat Commun
. 2022 Jul;
13(1):3882.
PMID: 35794100
Mitochondrial dynamics can regulate Major Histocompatibility Complex (MHC)-I antigen expression by cancer cells and their immunogenicity in mice and in patients with malignancies. A crucial role in the mitochondrial fragmentation...
4.
Lei X, Ou Z, Yang Z, Zhong J, Zhu Y, Tian J, et al.
Clin Cancer Res
. 2021 Apr;
27(13):3757-3771.
PMID: 33811153
Purpose: The limited efficacy of chimeric antigen receptor (CAR) T-cell therapies with solid malignancies prompted us to test whether epigenetic therapy could enhance the antitumor activity of B7-H3.CAR T cells...
5.
Fan S, Tian T, Lv X, Lei X, Yang Z, Liu M, et al.
iScience
. 2020 Jan;
23(2):100835.
PMID: 32000125
Cisplatin-based neoadjuvant chemotherapy has been shown to improve survival in patients with squamous cell carcinoma (SCC), but clinical biomarkers to predict chemosensitivity remain elusive. Here, we show the long noncoding...
6.
Chen W, Wang P, Lu Y, Jin T, Lei X, Liu M, et al.
Theranostics
. 2019 Sep;
9(20):5739-5754.
PMID: 31534516
MicroRNAs (miRNAs) have been recently found in the mitochondria, and were named "mitomiRs", but their function has remained elusive. Here, we aimed to assess the presence and function(s) of mitomiRs...
7.
Tian T, Lv X, Pan G, Lu Y, Chen W, He W, et al.
Clin Cancer Res
. 2019 Mar;
25(12):3673-3688.
PMID: 30885939
Purpose: The overall biological roles and clinical significance of most long noncoding RNAs (lncRNA) in chemosensitivity are not fully understood. We investigated the biological function, mechanism, and clinical significance of...
8.
Fan S, Tian T, Chen W, Lv X, Lei X, Zhang H, et al.
Cancer Res
. 2019 Jan;
79(6):1069-1084.
PMID: 30659020
miRNAs that translocate from the nucleus to mitochondria are referred to as mitochondrial microRNAs (mitomiR). mitomiRs have been shown to modulate the translational activity of the mitochondrial genome, yet their...
9.
Zeng B, Liao J, Zhang H, Fu S, Chen W, Pan G, et al.
Head Neck
. 2018 Dec;
41(1):230-238.
PMID: 30554457
Background: Gnathodiaphyseal dysplasia (GDD) is a rare skeletal disorder that has not been well studied. Methods: Sanger sequencing, whole-genome sequencing (WGS), and bioinformatics and structural modeling analyses were performed. Results:...
10.
Xie S, Yu X, Li Y, Ma H, Fan S, Chen W, et al.
Mol Ther
. 2018 Sep;
26(12):2766-2778.
PMID: 30217729
Neurotropic infiltrative growth and distant metastasis are the main causes of death in salivary adenoid cystic carcinoma (SACC) patients. Long noncoding RNAs (lncRNAs) are involved in many human neoplasms, however,...