Gunjan D Manocha
Overview
Explore the profile of Gunjan D Manocha including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
261
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Recent Articles
1.
Jurivich D, Van Eck R, Wood J, Snustad D, Holloway J, Langendoen D, et al.
J Am Geriatr Soc
. 2024 May;
72 Suppl 3:S82-S89.
PMID: 38720422
Background: Serious games enhance learner engagement and knowledge, yet few medical education games target older adults' healthcare. Addressing this gap, we developed Geri-POP (Geriatrics Population Health), focusing on the Age-Friendly...
2.
Trivedi R, Knopf B, Rakoczy S, Manocha G, Brown-Borg H, Jurivich D
Biogerontology
. 2023 Sep;
25(1):147-160.
PMID: 37707683
Brain aging is a major risk factor for cognitive diseases such as Alzheimer's disease (AD) and vascular dementia. The rate of aging and age-related pathology are modulated by stress responses...
3.
Trivedi R, Knopf B, Tripathi J, Rakoczy S, Manocha G, Brown-Borg H, et al.
Geroscience
. 2021 Apr;
43(4):1921-1934.
PMID: 33846884
How the heat shock axis, repair pathways, and proteostasis impact the rate of aging is not fully understood. Recent reports indicate that normal aging leads to a 50% change in...
4.
Sohrabi M, Floden A, Manocha G, Klug M, Combs C
Front Cell Neurosci
. 2020 Jul;
14:200.
PMID: 32719587
Aging is a major risk factor for Alzheimer's disease (AD). Insulin-like growth factor-1 receptor (IGF-1R) regulates general aging and lifespan. However, the contribution of IGF-1 to age-related AD pathology and...
5.
Jurivich D, Manocha G, Trivedi R, Lizakowski M, Rakoczy S, Brown-Borg H
J Gerontol A Biol Sci Med Sci
. 2019 Oct;
75(10):1846-1852.
PMID: 31612204
Age-dependent perturbation of the cellular stress response affects proteostasis and other key functions relevant to cellular action and survival. Central to age-related changes in the stress response is loss of...
6.
Jurivich D, Manocha G
J Invest Surg
. 2019 Oct;
34(5):545-546.
PMID: 31588819
No abstract available.
7.
Manocha G, Floden A, Miller N, Smith A, Nagamoto-Combs K, Saito T, et al.
Neurobiol Aging
. 2019 Jul;
81:166-176.
PMID: 31284126
The amyloid beta (Aβ) peptide is associated with the neurodegenerative and inflammatory changes in brains affected by Alzheimer's disease (AD). We hypothesized that the enteric nervous system also produces Aβ...
8.
Kulas J, Franklin W, Smith N, Manocha G, Puig K, Nagamoto-Combs K, et al.
Am J Physiol Endocrinol Metab
. 2018 Nov;
316(1):E106-E120.
PMID: 30422705
The amyloid precursor protein (APP) is a type I transmembrane glycoprotein widely studied for its role as the source of β-amyloid peptide, accumulation of which is causal in at least...
9.
Kulas J, Hettwer J, Sohrabi M, Melvin J, Manocha G, Puig K, et al.
Environ Pollut
. 2018 May;
241:279-288.
PMID: 29843010
Environmental exposure to air pollution has been linked to a number of health problems including organ rejection, lung damage and inflammation. While the deleterious effects of air pollution in adult...
10.
Manocha G, Ghatak A, Puig K, Kraner S, Norris C, Combs C
J Alzheimers Dis
. 2017 May;
58(3):775-787.
PMID: 28505967
Alzheimer's disease (AD) brains are characterized by fibrillar amyloid-β (Aβ) peptide containing plaques and associated reactive microglia. The proinflammatory phenotype of the microglia suggests that they may negatively affect disease...