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Guillem Sanchez Sanchez

Explore the profile of Guillem Sanchez Sanchez including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 78
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Recent Articles
1.
Billiet L, Jansen H, Pille M, Boehme L, Sanchez Sanchez G, De Cock L, et al.
Eur J Immunol . 2024 Sep; 54(12):e2451265. PMID: 39246170
In vitro cultures remain crucial for studying the fundamental mechanisms of human T-cell development. Here, we introduce a novel in vitro cultivation system based on ThymoSpheres (TS): dense spheroids consisting...
2.
Gong M, Myster F, Azouz A, Sanchez Sanchez G, Li S, Charloteaux B, et al.
Proc Natl Acad Sci U S A . 2024 Aug; 121(32):e2404536121. PMID: 39088396
Alcelaphine gammaherpesvirus 1 (AlHV-1) asymptomatically persists in its natural host, the wildebeest. However, cross-species transmission to cattle results in the induction of an acute and lethal peripheral T cell lymphoma-like...
3.
Giannoni E, Sanchez Sanchez G, Verdebout I, Papadopoulou M, Rezwani M, Ahmed R, et al.
Eur J Immunol . 2024 Jul; 54(10):e2451190. PMID: 39072722
Sepsis affects 25 million children per year globally, leading to 2.9 million deaths and substantial disability in survivors. Extensive characterization of interactions between the host and bacteria in children is...
4.
Sanchez Sanchez G, Emmrich S, Georga M, Papadaki A, Kossida S, Seluanov A, et al.
Nat Commun . 2024 May; 15(1):4248. PMID: 38762584
The naked mole-rat (Heterocephalus glaber) is a long-lived rodent species showing resistance to the development of cancer. Although naked mole-rats have been reported to lack natural killer (NK) cells, γδ...
5.
Ingels J, De Cock L, Stevens D, Mayer R, Thery F, Sanchez Sanchez G, et al.
Cell Rep Med . 2024 Apr; 5(5):101516. PMID: 38626769
Non-small cell lung cancer (NSCLC) is known for high relapse rates despite resection in early stages. Here, we present the results of a phase I clinical trial in which a...
6.
Le Moine M, Azouz A, Sanchez Sanchez G, Dejolier S, Nguyen M, Thomas S, et al.
Cell Rep . 2023 Aug; 42(8):112876. PMID: 37543948
The co-inhibitory programmed death (PD)-1 signaling pathway plays a major role in the context of tumor-specific T cell responses. Conversely, it also contributes to the maintenance of peripheral tolerance, as...
7.
Pille M, Avila J, Sanchez Sanchez G, Goetgeluk G, De Munter S, Jansen H, et al.
Front Immunol . 2023 Jun; 14:1188099. PMID: 37350958
The Wiskott-Aldrich syndrome (WAS) is an X-linked primary immune deficiency caused by a mutation in the WAS gene. This leads to altered or absent WAS protein (WASp) expression and function...
8.
Billiet L, De Cock L, Sanchez Sanchez G, Mayer R, Goetgeluk G, De Munter S, et al.
J Exp Med . 2023 Mar; 220(6). PMID: 36939517
In the human thymus, a CD10+ PD-1+ TCRαβ+ differentiation pathway diverges from the conventional single positive T cell lineages at the early double-positive stage. Here, we identify the progeny of...
9.
Sanchez Sanchez G, Tafesse Y, Papadopoulou M, Vermijlen D
Immunol Rev . 2023 Jan; 315(1):89-107. PMID: 36625367
While γδ T cells are present virtually in all vertebrates, there is a remarkable lack of conservation of the TRG and TRD loci underlying the generation of the γδ T...
10.
Sanchez Sanchez G, Vermijlen D
J Exp Med . 2022 Dec; 220(2). PMID: 36520517
In the mouse, γδ IL17 cells are poised to make IL-17, and these cells have been involved in various infection and cancer models. Edwards et al. (2022. J. Exp. Med.https://doi.org/10.1084/jem.20211431)...