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Guillaume P Ramstein

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Recent Articles
1.
Li T, Xu H, Teng S, Suo M, Bahitwa R, Xu M, et al.
Proc Natl Acad Sci U S A . 2024 Jun; 121(26):e2319811121. PMID: 38889146
Rational design of plant -regulatory DNA sequences without expert intervention or prior domain knowledge is still a daunting task. Here, we developed PhytoExpr, a deep learning framework capable of predicting...
2.
Wu Y, Li D, Hu Y, Li H, Ramstein G, Zhou S, et al.
Cell . 2023 May; 186(11):2313-2328.e15. PMID: 37146612
Hybrid potato breeding will transform the crop from a clonally propagated tetraploid to a seed-reproducing diploid. Historical accumulation of deleterious mutations in potato genomes has hindered the development of elite...
3.
Ramstein G, Buckler E
Genome Biol . 2022 Sep; 23(1):183. PMID: 36050782
Background: Crop improvement through cross-population genomic prediction and genome editing requires identification of causal variants at high resolution, within fewer than hundreds of base pairs. Most genetic mapping studies have...
4.
Lin M, Qiao P, Matschi S, Vasquez M, Ramstein G, Bourgault R, et al.
Plant Physiol . 2022 May; 189(4):2144-2158. PMID: 35512195
The cuticle, a hydrophobic layer of cutin and waxes synthesized by plant epidermal cells, is the major barrier to water loss when stomata are closed. Dissecting the genetic architecture of...
5.
Giri A, Khaipho-Burch M, Buckler E, Ramstein G
PLoS Genet . 2021 Oct; 17(10):e1009568. PMID: 34606492
Genomic prediction typically relies on associations between single-site polymorphisms and traits of interest. This representation of genomic variability has been successful for predicting many complex traits. However, it usually cannot...
6.
Wu D, Tanaka R, Li X, Ramstein G, Cu S, Hamilton J, et al.
G3 (Bethesda) . 2021 Mar; 11(4). PMID: 33677522
Despite its importance to plant function and human health, the genetics underpinning element levels in maize grain remain largely unknown. Through a genome-wide association study in the maize Ames panel...
7.
Jensen S, Charles J, Muleta K, Bradbury P, Casstevens T, Deshpande S, et al.
Plant Genome . 2020 Oct; 13(1):e20009. PMID: 33016627
Successful management and utilization of increasingly large genomic datasets is essential for breeding programs to accelerate cultivar development. To help with this, we developed a Sorghum bicolor Practical Haplotype Graph...
8.
Ramstein G, Larsson S, Cook J, Edwards J, Ersoz E, Flint-Garcia S, et al.
Genetics . 2020 Mar; 215(1):215-230. PMID: 32152047
Single-cross hybrids have been critical to the improvement of maize ( L.), but the characterization of their genetic architectures remains challenging. Previous studies of hybrid maize have shown the contribution...
9.
Ramstein G, Casler M
G3 (Bethesda) . 2019 Jan; 9(3):789-805. PMID: 30651285
Genomic prediction is a useful tool to accelerate genetic gain in selection using DNA marker information. However, this technology typically relies on standard prediction procedures, such as genomic BLUP, that...
10.
Ramstein G, Jensen S, Buckler E
Theor Appl Genet . 2018 Dec; 132(3):559-567. PMID: 30547185
In the past, plant breeding has undergone three major transformations and is currently transitioning to a new technological phase, Breeding 4. This phase is characterized by the development of methods...