Guiling Li
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Explore the profile of Guiling Li including associated specialties, affiliations and a list of published articles.
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Articles
177
Citations
2789
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Recent Articles
1.
Guo X, Qiao X, Li X, Zhou W, Liu C, Yu F, et al.
Phytomedicine
. 2025 Mar;
140:156547.
PMID: 40054175
Background: Parkinson's disease (PD) is a chronic neurodegenerative disorder primarily characterized by oxidative stress and dopaminergic neuron damage. While levodopa remains the cornerstone of PD treatment, its efficacy is limited...
2.
Yuan J, Su J, Zhong S, Yuan X, Zhu J, Lu S, et al.
Eur J Pharmacol
. 2025 Mar;
997:177464.
PMID: 40049578
Background: The treatment of ulcerative colitis (UC) remains a huge challenge worldwide. Dictamnine is a natural product derived from Dictamnus dasycarpus Turcz. root bark and possesses multi-pharmacological properties, including anti-inflammation...
3.
Niu X, Chang G, Xu N, Li R, Niu B, Mao R, et al.
ACS Nano
. 2025 Mar;
PMID: 40045827
Liver fibrosis, a complex process resulting from most chronic liver diseases, remains devoid of effective treatments. An increasing body of evidence links liver fibrosis to the "gut-liver axis", with disruptions...
4.
Chen Y, Su L, Liu H, Zhang T, Li G, Sun L, et al.
Food Chem
. 2025 Jan;
473:143111.
PMID: 39889640
Endogenous proteases, such as matrix metalloproteinase 1 (MMP-1), play critical roles in abalone muscle softening (myomalacia) via the decomposition of extracellular matrix, particularly collagen. However, the synergistic effect of endogenous...
5.
Chen B, Ye X, Chen L, Liu T, Li G, Sa C, et al.
Animal Model Exp Med
. 2025 Jan;
8(3):511-522.
PMID: 39854156
Background: Makorin ring finger protein 3 gene (MKRN3) gene mutation is the most common genetic cause of central precocious puberty (CPP) in children. Due to the lack of ideal MKRN3-modified...
6.
Chen W, Qiu J, Li P, Zhang Q, Li D, Li G, et al.
J Med Chem
. 2025 Jan;
68(3):3612-3625.
PMID: 39847528
Pyroptosis, an excellent form of immunogenic cell death that can effectively activate antitumor immune responses, is attracting considerable interest as a promising approach for cancer immunotherapy. Immunogenic pyroptosis can recruit...
7.
Li H, Xu Y, Jiao X, Xu Q, Peng Z, Tang Y, et al.
Med
. 2025 Jan;
100573.
PMID: 39827881
Background: It remains unclear whether adding CTLA-4 blockade to PD-1/PD-L1 blockade improves clinical outcomes in cervical cancer (CC). Methods: In this randomized, double-blind, placebo-controlled, phase 2 study (ClinicalTrials.gov: NCT04590599), patients...
8.
Zhang J, Yu W, Li G, Li G, Chen B, Wang L, et al.
ACS Nano
. 2025 Jan;
19(3):3676-3693.
PMID: 39813732
Blood-contacting medical devices can easily trigger immune responses, leading to thrombosis and hyperblastosis. Constructing microtexture that provides efficient antithrombotic and rapid reendothelialization performance on complex curved surfaces remains a pressing...
9.
Xu H, Yao X, He Z, Luo H, Li G, Guo J, et al.
Target Oncol
. 2025 Jan;
20(1):113-125.
PMID: 39806128
Background: Antiangiogenic inhibitors plus immune checkpoint inhibitors have synergistic antitumor activity and have improved treatment outcomes in patients with renal cell carcinoma (RCC). Objective: We report the RCC cohort from...
10.
Chen B, Sa C, Li G, Liu T, Liu K, Gu W, et al.
J Vis Exp
. 2025 Jan;
(214).
PMID: 39760406
With the advancement of scientific research, the demand for gene-edited rabbit models is increasing. However, there are limited pregnancy and feeding management systems for gene-edited rabbits, leading to low survival...