Guido H Falduto
Overview
Explore the profile of Guido H Falduto including associated specialties, affiliations and a list of published articles.
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14
Citations
57
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Recent Articles
1.
Pfeiffer A, Bandara G, Petersen J, Falduto G, Zimmerberg J, Metcalfe D, et al.
J Extracell Biol
. 2024 Jun;
3(1):e139.
PMID: 38938682
The receptor tyrosine kinase (RTK) KIT and its ligand stem cell factor (SCF) are essential for human mast cell (huMC) survival and proliferation. HuMCs expressing oncogenic KIT variants secrete large...
2.
Son A, Baral I, Falduto G, Schwartz D
Exp Mol Med
. 2024 Jun;
56(6):1331-1339.
PMID: 38825637
Interleukin-9 (IL-9) is a multifunctional cytokine with roles in a broad cross-section of human diseases. Like many cytokines, IL-9 is transcriptionally regulated by a group of noncoding regulatory elements (REs)...
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4.
Son A, Meylan F, Gomez-Rodriguez J, Kaul Z, Sylvester M, Falduto G, et al.
Nat Immunol
. 2023 Oct;
24(12):2164.
PMID: 37821709
No abstract available.
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6.
Son A, Meylan F, Gomez-Rodriguez J, Kaul Z, Sylvester M, Falduto G, et al.
Nat Immunol
. 2023 Apr;
24(6):1036-1048.
PMID: 37106040
Allergic diseases are a major global health issue. Interleukin (IL)-9-producing helper T (T9) cells promote allergic inflammation, yet T9 cell effector functions are incompletely understood because their lineage instability makes...
7.
Bandara G, Falduto G, Luker A, Bai Y, Pfeiffer A, Lack J, et al.
Front Immunol
. 2023 Apr;
14:1078958.
PMID: 37025992
The HMC-1.2 human mast cell (huMC) line is often employed in the study of attributes of neoplastic huMCs as found in patients with mastocytosis and their sensitivity to interventional drugs...
8.
Pfeiffer A, Petersen J, Falduto G, Anderson D, Zimmerberg J, Metcalfe D, et al.
J Extracell Vesicles
. 2022 Oct;
11(10):e12272.
PMID: 36239715
Activating mutations in the receptor KIT promote the dysregulated proliferation of human mast cells (huMCs). The resulting neoplastic huMCs secrete extracellular vesicles (EVs) that can transfer oncogenic KIT among other...
9.
Snider D, Arthur G, Falduto G, Olivera A, Ehrhardt-Humbert L, Smith E, et al.
Mol Ther
. 2021 Aug;
30(1):295-310.
PMID: 34371183
Activating mutations in c-KIT are associated with the mast cell (MC) clonal disorders cutaneous mastocytosis and systemic mastocytosis and its variants, including aggressive systemic mastocytosis, MC leukemia, and MC sarcoma....
10.
Vila C, Saracino M, Lombardo T, Falduto G, Diaz M, Calcagno M, et al.
Parasite Immunol
. 2021 Jan;
43(4):e12820.
PMID: 33434287
The goal of this study was to analyse the effects of a protein-deficient (PD) diet on antibody-dependent cell-mediated cytotoxicity (ADCC) in vitro against newborn larvae (NBL) of Trichinella spiralis in...