Gui-Lan Chen
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Explore the profile of Gui-Lan Chen including associated specialties, affiliations and a list of published articles.
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Articles
52
Citations
394
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Recent Articles
1.
Wan J, Hu Z, Zhu H, Li J, Zheng Z, Deng Z, et al.
Pharmacol Res
. 2025 Feb;
213:107648.
PMID: 39923924
Sphingolipids are critical components of cellular membranes that play a pivotal role in modulating ion channel function by forming lipid rafts that stabilize and localize these channels. These lipids regulate...
2.
Zhou J, Wang C, Li J, Chen G, Tang X, Li F, et al.
Hemoglobin
. 2025 Jan;
:1-3.
PMID: 39748151
Microcytosis of red cells and mild anemia are common in thalassemia carriers but those phenotypes are not specific. It is really a challenge for clinical interpretation of those variants. Co-segregation...
3.
Early Prenatal Detection of Recessive Split-hand/Foot Malformation Caused by a Homozygous Variant of
Chen G, Zhen L, Li D
J Med Ultrasound
. 2024 Sep;
32(3):271-272.
PMID: 39310870
No abstract available.
4.
Chen G, Li J, Chen X, Liu J, Zhang Q, Liu J, et al.
J Clin Invest
. 2023 Dec;
134(5).
PMID: 38127458
Pulmonary surfactant is a lipoprotein complex lining the alveolar surface to decrease the surface tension and facilitate inspiration. Surfactant deficiency is often seen in premature infants and in children and...
5.
Chen X, Wang N, Liu J, Zeng B, Chen G
Biochem Biophys Res Commun
. 2023 Oct;
683:149111.
PMID: 37857161
The transmembrane 63 (TMEM63) family of proteins are originally identified as homologs of the osmosensitive calcium-permeable (OSCA) channels in plants. Mechanosensitivity of OSCA and TMEM63 proteins are recently demonstrated in...
6.
Tang X, Jiang F, Li J, Lin X, Zhou J, Wan J, et al.
Ann Hum Genet
. 2023 Sep;
87(6):316-325.
PMID: 37771257
Background: To evaluate the value of the real-time PCR-based multicolor melting curve analysis (MMCA) with an automatic analysis system used in a mass thalassemia screening and prenatal diagnosis program. Methods:...
7.
Chen G, Li J, Zhang J, Zeng B
Cells
. 2023 Jul;
12(14).
PMID: 37508534
Ion channels are the second largest class of drug targets after G protein-coupled receptors. In addition to well-recognized ones like voltage-gated Na/K/Ca channels in the heart and neurons, novel ion...
8.
Chen G, Zeng B, Jiang H, Daskoulidou N, Saurabh R, Chitando R, et al.
Biomolecules
. 2023 Jun;
13(6).
PMID: 37371532
An elevated level of circulating homocysteine (Hcy) has been regarded as an independent risk factor for cardiovascular disease; however, the clinical benefit of Hcy lowering-therapy is not satisfying. To explore...
9.
Wang N, Li J, Zeng B, Chen G
Biomolecules
. 2023 May;
13(5).
PMID: 37238688
Sphingosine-1-phosphate (S1P) is an important sphingolipid molecule involved in regulating cardiovascular functions in physiological and pathological conditions by binding and activating the three G protein-coupled receptors (S1PR1, S1PR2, and S1PR3)...
10.
Yang Y, Chen G, Li D
Eur J Obstet Gynecol Reprod Biol
. 2023 Apr;
285:206-207.
PMID: 37032249
No abstract available.