Guanzhao Wu
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Explore the profile of Guanzhao Wu including associated specialties, affiliations and a list of published articles.
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21
Citations
100
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Recent Articles
1.
Kong D, Meng L, Lin P, Wu G
Future Med Chem
. 2025 Feb;
17(5):591-605.
PMID: 39931801
Neurodegenerative diseases are characterized by impairments in movement and cognitive functions. These disorders are frequently associated with the accumulation of misfolded protein aggregates, which present significant challenges for treatment with...
2.
Wang Z, Sun Y, Bai Z, Li M, Kong D, Wu G
Mov Disord
. 2025 Jan;
PMID: 39838927
Background: Mitochondrial dysfunction is increasingly recognized as a key factor in neurodegenerative diseases (NDDs), underscoring the therapeutic potential of targeting mitochondria-related genes. This study aimed to identify novel biomarkers and...
3.
Bai Z, Wang Z, Li M, Kong D, Wu G
Brain Behav
. 2024 Nov;
14(11):e70151.
PMID: 39552109
Objectives: This study leveraged the China Health and Retirement Longitudinal Study (CHARLS) to explore the association between diabetes and stroke in middle-aged and older adults in East Asia and assess...
4.
Li M, Kong D, Meng L, Wang Z, Bai Z, Wu G
RSC Adv
. 2024 Sep;
14(41):29789-29799.
PMID: 39301232
Neuroinflammation and mitochondrial function are crucial for neuronal function and survival. SS-31 is a novel mitochondria-targeted peptide antioxidant that reduces mitochondrial reactive oxygen species production, increases ATP generation, protects the...
5.
Zhang C, Wu G
Talanta
. 2024 Aug;
279:126622.
PMID: 39089081
Adenosine-5'-triphosphate (ATP) is a critical biological molecule that functions as the primary energy currency within cells. ATP synthesis occurs in the mitochondria, and variations in its concentration can significantly influence...
6.
Liu J, Ni Y, Zhou K, Wu G, Hu L, Zhu T, et al.
Chem Biol Drug Des
. 2024 Jul;
104(1):e14583.
PMID: 38991995
In this work, a series of curcumin derivatives (1a-1h, 2a-2g, and 3a-3c) were synthesized for the suppression of castration-resistant prostate cancer cells. All synthesized compounds were characterized by H NMR,...
7.
Meng L, Wu G
RSC Adv
. 2023 Jul;
13(30):20476-20485.
PMID: 37435377
Mitochondrial disorders are observed in various human diseases, including rare genetic disorders and complex acquired pathologies. Recent advances in molecular biological techniques have dramatically expanded the understanding of multiple pathomechanisms...
8.
Fu Q, Li T, Zhang C, Ma X, Meng L, Liu L, et al.
Cell Commun Signal
. 2023 May;
21(1):95.
PMID: 37143096
The higher prevalence of metabolic syndrome (MetS) in women after menopause is associated with a decrease in circulating 17β-oestradiol. To explore novel treatments for MetS in women with oestrogen deficiency,...
9.
Liu X, Meng L, Wang Z, Yu Z, Zhang C, Liu L, et al.
Eur J Med Chem
. 2023 Feb;
250:115207.
PMID: 36796298
All-in-one nano theranostics integrating accurate diagnosis and combined therapy is promising for high-efficacy tumor treatment and receiving significant attention. In this study, we develop photo-controlled release liposomes with nucleic acid-triggered...
10.
Wang Z, Meng L, Liu X, Zhang L, Yu Z, Wu G
Eur J Med Chem
. 2022 Sep;
243:114700.
PMID: 36058089
Atropisomers are stereoisomers with axial chirality arising from restricted rotation around a single bond. Lots of representatives of this class of axially chiral compounds exhibit remarkable biological properties for protein...