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Guangsheng Pei

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Articles 77
Citations 881
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Recent Articles
1.
Sheng W, Huang L, Gu X, Wang Y, Jiang M, Hu C, et al.
Clin Microbiol Infect . 2024 Dec; PMID: 39662822
Objectives: The objectives of this study are to analyse the effect and safety of procalcitonin (PCT)-guided antibiotic therapy in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods:...
2.
Jiang J, Liu Y, Qin J, Chen J, Wu J, Pizzi M, et al.
Nat Commun . 2024 Aug; 15(1):7312. PMID: 39181865
Recent advances in spatial transcriptomics (ST) techniques provide valuable insights into cellular interactions within the tumor microenvironment (TME). However, most analytical tools lack consideration of histological features and rely on...
3.
Cheng X, Dai E, Wu J, Flores N, Chu Y, Wang R, et al.
Gastroenterology . 2024 Aug; 167(7):1345-1357. PMID: 39097198
Background & Aims: Metastases from gastric adenocarcinoma (GAC) lead to high morbidity and mortality. Developing innovative and effective therapies requires a comprehensive understanding of the tumor and immune biology of...
4.
Dai Y, Itai T, Pei G, Yan F, Chu Y, Jiang X, et al.
HGG Adv . 2024 Jun; 5(3):100322. PMID: 38944832
No abstract available.
5.
Dai Y, Itai T, Pei G, Yan F, Chu Y, Jiang X, et al.
HGG Adv . 2024 May; 5(3):100312. PMID: 38796699
Orofacial clefts (OFCs) are among the most common human congenital birth defects. Previous multiethnic studies have identified dozens of associated loci for both cleft lip with or without cleft palate...
6.
Pei G, Guo L, Liang S, Chen F, Ma N, Bai J, et al.
Respiration . 2024 Apr; 103(8):461-479. PMID: 38663359
Introduction: Although long-term macrolide antibiotics could reduce the recurrent exacerbation of chronic obstructive pulmonary disease (COPD), the side effect of bacterial resistance and the impact on the microbiota remain concerning....
7.
Han G, Sinjab A, Rahal Z, Lynch A, Treekitkarnmongkol W, Liu Y, et al.
Nature . 2024 Mar; 628(8006):E1. PMID: 38499683
No abstract available.
8.
Han G, Sinjab A, Rahal Z, Lynch A, Treekitkarnmongkol W, Liu Y, et al.
Nature . 2024 Feb; 627(8004):656-663. PMID: 38418883
Understanding the cellular processes that underlie early lung adenocarcinoma (LUAD) development is needed to devise intervention strategies. Here we studied 246,102 single epithelial cells from 16 early-stage LUADs and 47...
9.
Yin L, Hu X, Pei G, Tang M, Zhou Y, Zhang H, et al.
Life Sci Alliance . 2024 Feb; 7(4). PMID: 38316463
Radiation therapy (RT) is one of the most commonly used anticancer therapies. However, the landscape of cellular response to irradiation, especially to a single high-dose irradiation, remains largely unknown. In...
10.
Yan F, Suzuki A, Iwaya C, Pei G, Chen X, Yoshioka H, et al.
Nat Commun . 2024 Jan; 15(1):821. PMID: 38280850
Perturbations in gene regulation during palatogenesis can lead to cleft palate, which is among the most common congenital birth defects. Here, we perform single-cell multiome sequencing and profile chromatin accessibility...