Guan-Sheng Liu
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Explore the profile of Guan-Sheng Liu including associated specialties, affiliations and a list of published articles.
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20
Citations
236
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Recent Articles
1.
Zhang Y, Huynh J, Liu G, Ballweg R, Aryeh K, Paek A, et al.
PLoS Comput Biol
. 2019 Sep;
15(9):e1007158.
PMID: 31498788
Chemotherapy resistance is a major challenge to the effective treatment of cancer. Thus, a systematic pipeline for the efficient identification of effective combination treatments could bring huge biomedical benefit. In...
2.
Liu G, Ballweg R, Ashbaugh A, Zhang Y, Facciolo J, Cushion M, et al.
BMC Syst Biol
. 2019 Aug;
13(1):40.
PMID: 31405372
It was highlighted that the original article [1] contained errors in the figures and their legends and by extension the in-text figure citations. This Corrections article shows the correct figures...
3.
Gardner G, Travers J, Qian J, Liu G, Haghighi K, Robbins N, et al.
JACC Basic Transl Sci
. 2019 May;
4(2):188-199.
PMID: 31061921
Cardiomyocyte-specific increases in phosphorylated Hsp20 (S16D-Hsp20) to levels similar to those observed in human failing hearts are associated with early fibrotic remodeling and depressed left ventricular function, symptoms which progress...
4.
Liu G, Ballweg R, Ashbaugh A, Zhang Y, Facciolo J, Cushion M, et al.
BMC Syst Biol
. 2018 Jul;
12(1):77.
PMID: 30016951
Background: The yeast-like fungi Pneumocystis, resides in lung alveoli and can cause a lethal infection known as Pneumocystis pneumonia (PCP) in hosts with impaired immune systems. Current therapies for PCP,...
5.
Liu G, Gardner G, Adly G, Jiang M, Cai W, Lam C, et al.
J Cell Mol Med
. 2018 May;
22(8):3911-3919.
PMID: 29761889
Heat shock protein 20 (Hsp20) has been shown to be a critical regulator of cardiomyocyte survival upon cardiac stress. In this study, we investigated the functional significance of a novel...
6.
Li Y, Cai W, Wang L, Liu G, Paul C, Jiang L, et al.
DNA Cell Biol
. 2018 Feb;
37(5):432-441.
PMID: 29461873
HCLS1 Associated Protein X-1 (HAX1) promotes cell survival through attenuation of the damaged signals from endoplasmic reticulum and mitochondria, which are known as prominent intracellular compartments for the autophagic process...
7.
Bidwell P, Liu G, Nagarajan N, Lam C, Haghighi K, Gardner G, et al.
J Mol Cell Cardiol
. 2017 Nov;
114:220-233.
PMID: 29169992
Ischemia/reperfusion injury is associated with contractile dysfunction and increased cardiomyocyte death. Overexpression of the hematopoietic lineage substrate-1-associated protein X-1 (HAX-1) has been shown to protect from cellular injury but the...
8.
Liu G, Zhu H, Cai W, Wang X, Jiang M, Essandoh K, et al.
Autophagy
. 2017 Nov;
14(1):80-97.
PMID: 29157081
HSPB6/Hsp20 (heat shock protein family B [small] member 6) has emerged as a novel cardioprotector against stress-induced injury. We identified a human mutant of HSPB6 (HSPB6) exclusively present in dilated...
9.
Pollak A, Haghighi K, Kunduri S, Arvanitis D, Bidwell P, Liu G, et al.
Proc Natl Acad Sci U S A
. 2017 Aug;
114(34):9098-9103.
PMID: 28784772
Precise Ca cycling through the sarcoplasmic reticulum (SR), a Ca storage organelle, is critical for proper cardiac muscle function. This cycling initially involves SR release of Ca via the ryanodine...
10.
Cai W, Liu G, Wang L, Paul C, Wen Z, Wang Y
Stem Cells Int
. 2016 Nov;
2016:6193419.
PMID: 27799944
Cardiac regeneration is a homeostatic cardiogenic process by which the sections of malfunctioning adult cardiovascular tissues are repaired and renewed employing a combination of both cardiomyogenesis and angiogenesis. Unfortunately, while...