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Grzegorz Palczewski

Explore the profile of Grzegorz Palczewski including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 221
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Recent Articles
1.
McCall K, Walter D, Patton A, Thuma J, Courreges M, Palczewski G, et al.
J Inflamm Res . 2023 Nov; 16:5339-5366. PMID: 38026235
Purpose: Non-alcoholic fatty liver disease (NAFLD), recently renamed metabolic (dysfunction) associated fatty liver disease (MAFLD), is the most common chronic liver disease in the United States. Presently, there is an...
2.
Zafarullah M, Palczewski G, Rivera S, Hessl D, Tassone F
FASEB J . 2020 Nov; 34(12):16676-16692. PMID: 33131090
Fragile X-associated Tremor/Ataxia Syndrome (FXTAS) is a neurodegenerative disorder associated with the FMR1 premutation. It is currently unknown when, and if, individual premutation carriers will develop FXTAS. Thus, with the...
3.
Widjaja-Adhi M, Palczewski G, Dale K, Knauss E, Kelly M, Golczak M, et al.
Proc Natl Acad Sci U S A . 2017 Oct; 114(43):11530-11535. PMID: 29073082
The intestinal epithelium is a major site for the conversion of dietary β-carotene to retinaldehyde by the enzyme BCO1. The majority of retinaldehyde is further metabolized to retinol (vitamin A),...
4.
Palczewski G, Widjaja-Adhi M, Amengual J, Golczak M, von Lintig J
J Lipid Res . 2016 Jul; 57(9):1684-95. PMID: 27389691
Carotenoids affect a rich variety of physiological functions in nature and are beneficial for human health. However, knowledge about their biological action and the consequences of their dietary accumulation in...
5.
Kelly M, Widjaja-Adhi M, Palczewski G, von Lintig J
FASEB J . 2016 May; 30(8):2985-95. PMID: 27189978
Vitamin A bound to retinol binding protein 4 (RBP4) constitutes the major transport mode for retinoids in fasting circulation. Emerging evidence suggests that membrane protein, STRA6 (stimulated by retinoic acid...
6.
Babino D, Palczewski G, Widjaja-Adhi M, Kiser P, Golczak M, von Lintig J
J Biol Chem . 2015 Aug; 290(41):24844-57. PMID: 26307071
A family of enzymes collectively referred to as carotenoid cleavage oxygenases is responsible for oxidative conversion of carotenoids into apocarotenoids, including retinoids (vitamin A and its derivatives). A member of...
7.
Palczewski G, Amengual J, Hoppel C, von Lintig J
FASEB J . 2014 Jul; 28(10):4457-69. PMID: 25002123
The critical role of retinoids (vitamin A and its derivatives) for vision, reproduction, and survival has been well established. Vitamin A is produced from dietary carotenoids such as β-carotene by...
8.
Lobo G, Amengual J, Palczewski G, Babino D, von Lintig J
Biochim Biophys Acta . 2011 May; 1821(1):78-87. PMID: 21569862
Humans depend on a dietary intake of lipids to maintain optimal health. Among various classes of dietary lipids, the physiological importance of carotenoids is still controversially discussed. On one hand,...