Gregory M Vercellotti
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Explore the profile of Gregory M Vercellotti including associated specialties, affiliations and a list of published articles.
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107
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3319
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Recent Articles
1.
Beckman J, Zhang P, Nguyen J, Hebbel R, Vercellotti G, Belcher J
Front Immunol
. 2025 Jan;
15():1493904.
PMID: 39776915
Sickle cell disease (SCD) is a devastating hemolytic disease, marked by recurring bouts of painful vaso-occlusion, leading to tissue damage from ischemia/reperfusion pathophysiology. Central to this process are oxidative stress,...
2.
Argueta D, Tran H, Goel Y, Nguyen A, Nguyen J, Kiven S, et al.
Life Sci Alliance
. 2024 Sep;
7(11).
PMID: 39242155
Sickle cell disease (SCD) is the most common inherited monogenetic disorder. Chronic and acute pain are hallmark features of SCD involving neural and vascular injury and inflammation. Mast cells reside...
3.
Dimitrov M, Merkle S, Cao Q, Tryon R, Vercellotti G, Holtan S, et al.
Transplant Cell Ther
. 2024 Jul;
30(10):1005.e1-1005.e17.
PMID: 39002862
Background: Dyskeratosis congenita/telomere biology disorders (DC/TBD) often manifest as bone marrow failure (BMF) or myelodysplastic syndrome (MDS). Allogeneic hematopoietic cell transplant (alloHCT) rescues hematologic complications, but radiation and alkylator-based conditioning...
4.
Pace A, Steiner M, Vercellotti G, Somani A
Front Transplant
. 2024 Jul;
2:1130941.
PMID: 38993867
An understanding of the interplay between both donor endothelial progenitors and the recipient endothelium (in the case of hematopoietic cell transplant) and recipient endothelial provenance upon the established donor endothelium...
5.
Aleman M, Arepally G, Baglin T, Buitrago L, Davizon-Castillo P, Dayal S, et al.
Res Pract Thromb Haemost
. 2024 May;
8(3):102395.
PMID: 38699410
The University of North Carolina Symposia on Hemostasis began in 2002, with The First Symposium on Hemostasis with a Special Focus on FVIIa and Tissue Factor. They have occurred biannually...
6.
Xu J, Vercellotti G
Hematology Am Soc Hematol Educ Program
. 2023 Dec;
2023(1):107-113.
PMID: 38066891
Hemoglobin S (HbS) polymerization, red blood cell (RBC) sickling, chronic anemia, and vaso-occlusion are core to sickle cell disease (SCD) pathophysiology. Pyruvate kinase (PK) activators are a novel class of...
7.
Ivy Z, Belcher J, Khasabova I, Chen C, Juliette J, Abdulla F, et al.
Blood
. 2023 Sep;
142(22):1918-1927.
PMID: 37774369
Vaso-occlusive pain episodes (VOE) cause severe pain in patients with sickle cell disease (SCD). Vaso-occlusive events promote ischemia/reperfusion pathobiology that activates complement. We hypothesized that complement activation is linked to...
8.
Belcher J, Nataraja S, Abdulla F, Zhang P, Chen C, Nguyen J, et al.
Front Med (Lausanne)
. 2023 May;
10:1101501.
PMID: 37144034
In sickle cell disease (SCD), heme released during intravascular hemolysis promotes oxidative stress, inflammation, and vaso-occlusion. Conversely, free heme can also activate expression of antioxidant and globin genes. Heme binds...
9.
Habib A, Shaaban A, Thompson J, Chinnakotla S, Martin C, Vercellotti G
J Investig Med High Impact Case Rep
. 2023 Mar;
11:23247096231159812.
PMID: 36914978
Iron overload cardiomyopathy has been described in patients who develop acute heart failure after liver transplantation but few reports of this are available. We present a case of a patient...
10.
Beckman J, DaSilva A, Aronovich E, Nguyen A, Nguyen J, Hargis G, et al.
J Thromb Haemost
. 2023 Feb;
21(5):1366-1380.
PMID: 36738826
Background: Vascular activation is characterized by increased proinflammatory, pro thrombotic, and proadhesive signaling. Several chronic and acute conditions, including Bcr-abl-negative myeloproliferative neoplasms (MPNs), graft-vs-host disease, and COVID-19 have been noted...