Gregg B Morin
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Explore the profile of Gregg B Morin including associated specialties, affiliations and a list of published articles.
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91
Citations
5386
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Recent Articles
1.
Samarasekera G, Go N, Choutka C, Xu J, Takemon Y, Chan J, et al.
PLoS Biol
. 2025 Feb;
23(3):e3003034.
PMID: 39982959
Cell stress adaptation plays a key role in normal development and in various diseases including cancer. Caspases are activated in response to cell stress, and growing evidence supports their function...
2.
Shraim R, Mooney B, Conkrite K, Hamilton A, Morin G, Sorensen P, et al.
Bioinformatics
. 2025 Feb;
41(3).
PMID: 39932005
Motivation: Cancer remains a leading cause of mortality globally. Recent improvements in survival have been facilitated by the development of targeted and less toxic immunotherapies, such as chimeric antigen receptor...
3.
Ferrario C, Mackey J, Gelmon K, LeVasseur N, Sorensen P, Oo H, et al.
Clin Cancer Res
. 2024 Nov;
31(3):491-502.
PMID: 39576211
Purpose: Preclinical data motivate clinical evaluation of inhibitors of MAPK-interacting kinases 1 and 2 (MNK1/2). We conducted a phase 1b clinical trial to study target engagement and safety of tomivosertib,...
4.
Ghashghaei M, Liu Y, Ettles J, Bombaci G, Ramkumar N, Liu Z, et al.
Nat Commun
. 2024 Oct;
15(1):8674.
PMID: 39375334
No abstract available.
5.
Vallejos R, Zhantuyakova A, Negri G, Martin S, Spencer S, Thornton S, et al.
J Pathol
. 2024 Jul;
264(2):197-211.
PMID: 39081243
Low-grade serous ovarian carcinoma (LGSC) is a rare and lethal subtype of ovarian cancer. LGSC is pathologically, biologically, and clinically distinct from the more common high-grade serous ovarian carcinoma (HGSC)....
6.
Riley R, Negri G, Cheng S, Spencer Miko S, Morin R, Morin G
J Proteome Res
. 2024 Jun;
23(8):3704-3715.
PMID: 38943634
Proteome coverage and accurate protein quantification are both important for evaluating biological systems; however, compromises between quantification, coverage, and mass spectrometry (MS) resources are often necessary. Consequently, experimental parameters that...
7.
Shraim R, Mooney B, Conkrite K, Weiner A, Morin G, Sorensen P, et al.
bioRxiv
. 2024 Jun;
PMID: 38895237
Cancer remains a leading cause of mortality globally. Recent improvements in survival have been facilitated by the development of less toxic immunotherapies; however, identifying targets for immunotherapies remains a challenge...
8.
Ghashghaei M, Liu Y, Ettles J, Bombaci G, Ramkumar N, Liu Z, et al.
Nat Commun
. 2024 Mar;
15(1):2340.
PMID: 38491013
Protein synthesis is frequently deregulated during tumorigenesis. However, the precise contexts of selective translational control and the regulators of such mechanisms in cancer is poorly understood. Here, we uncovered CNOT3,...
9.
Pozner A, Li L, Verma S, Wang S, Barrott J, Nelson M, et al.
Nat Commun
. 2024 Feb;
15(1):1165.
PMID: 38326311
The t(X,17) chromosomal translocation, generating the ASPSCR1::TFE3 fusion oncoprotein, is the singular genetic driver of alveolar soft part sarcoma (ASPS) and some Xp11-rearranged renal cell carcinomas (RCCs), frustrating efforts to...
10.
Eskandari E, Negri G, Tan S, MacAldaz M, Ding S, Long J, et al.
Cell Death Discov
. 2024 Feb;
10(1):63.
PMID: 38321033
Mechanisms that regulate cell survival and proliferation are important for both the development and homeostasis of normal tissue, and as well as for the emergence and expansion of malignant cell...