Greg Foltz
Overview
Explore the profile of Greg Foltz including associated specialties, affiliations and a list of published articles.
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14
Citations
3168
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Recent Articles
1.
Ghosh D, Funk C, Caballero J, Shah N, Rouleau K, Earls J, et al.
Cell Syst
. 2017 Apr;
4(5):516-529.e7.
PMID: 28365151
We present a systems strategy that facilitated the development of a molecular signature for glioblastoma (GBM), composed of 33 cell-surface transmembrane proteins. This molecular signature, GBMSig, was developed through the...
2.
Schroeder B, Shah N, Rostad S, McCullough B, Aguedan B, Foltz G, et al.
J Neurosurg
. 2015 Oct;
124(5):1353-8.
PMID: 26473785
The authors report a case of multicentric glioblastoma multiforme (GBM) in which all 4 tumor foci were resected and evaluated using both comparative genomic hybridization array and RNA sequencing. Genetic...
3.
Shah N, Lankerovich M, Lee H, Yoon J, Schroeder B, Foltz G
BMC Genomics
. 2013 Nov;
14:818.
PMID: 24261984
Background: RNA-seq has spurred important gene fusion discoveries in a number of different cancers, including lung, prostate, breast, brain, thyroid and bladder carcinomas. Gene fusion discovery can potentially lead to...
4.
Brennan C, Verhaak R, McKenna A, Campos B, Noushmehr H, Salama S, et al.
Cell
. 2013 Oct;
155(2):462-77.
PMID: 24120142
We describe the landscape of somatic genomic alterations based on multidimensional and comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify several novel mutated genes as well as...
5.
Hothi P, Martins T, Chen L, Deleyrolle L, Yoon J, Reynolds B, et al.
Oncotarget
. 2012 Nov;
3(10):1124-36.
PMID: 23165409
Glioblastoma Multiforme (GBM) continues to have a poor patient prognosis despite optimal standard of care. Glioma stem cells (GSCs) have been implicated as the presumed cause of tumor recurrence and...
6.
Magalhaes J, Rostad S, Foltz G, Pytel P, Rodriguez F
Brain Tumor Pathol
. 2012 May;
30(2):93-8.
PMID: 22622671
Papillary tumor of the pineal region (PTPR) is a recently recognized entity. We present the pathologic findings of two cases of PTPR as examples, and discuss the presence of cellular...
7.
Foltz G, Yoon J, Lee H, Ma L, Tian Q, Hood L, et al.
Genes Cancer
. 2011 Jul;
1(1):81-90.
PMID: 21779426
Epigenetic inactivation of tumor suppressor genes is common in human cancer. Using a large-scale whole-genome approach in an earlier study, the authors identified epigenetically silenced genes with potential tumor suppressor...
8.
Shah N, Lin B, Sibenaller Z, Ryken T, Lee H, Yoon J, et al.
PLoS One
. 2011 Jan;
6(1):e16146.
PMID: 21249131
O⁶-methylguanine DNA-methyltransferase (MGMT) promoter methylation has been identified as a potential prognostic marker for glioblastoma patients. The relationship between the exact site of promoter methylation and its effect on gene...
9.
Panchalingam K, Paramchuk W, Chiang C, Shah N, Madan A, Hood L, et al.
Tissue Eng Part A
. 2009 Dec;
16(4):1169-77.
PMID: 20021271
Solid cancer tumors are thought to arise from aberrant stem cell populations, called cancer stem cells (CSCs). Hence, the development of effective cancer therapies may rely on developing methods that...
10.
Tu L, Foltz G, Lin E, Hood L, Tian Q
Curr Stem Cell Res Ther
. 2009 May;
4(2):147-53.
PMID: 19442199
Cancer stem cells (CSC), also called tumor initiating cells (TIC), are considered to be the origin of replicating malignant tumor cells in a variety of human cancers. Their presence in...