Greg B G Moorhead
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Explore the profile of Greg B G Moorhead including associated specialties, affiliations and a list of published articles.
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45
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Recent Articles
11.
Tran H, Nimick M, Uhrig R, Templeton G, Morrice N, Gourlay R, et al.
Plant J
. 2012 Mar;
71(2):263-72.
PMID: 22404109
It is now emerging that many proteins are regulated by a variety of covalent modifications. Using microcystin-affinity chromatography we have purified multiple protein phosphatases and their associated proteins from Arabidopsis...
12.
Silver D, Silva L, Issakidis-Bourguet E, Glaring M, Schriemer D, Moorhead G
FEBS J
. 2012 Mar;
280(2):538-48.
PMID: 22372537
Starch is the major carbohydrate reserve in plants, and is degraded for growth at night. Starch breakdown requires reversible glucan phosphorylation at the granule surface by novel dikinases and phosphatases....
13.
Templeton G, Nimick M, Morrice N, Campbell D, Goudreault M, Gingras A, et al.
Biochem J
. 2011 Jan;
435(1):73-83.
PMID: 21222654
PP1 (protein phosphatase 1) is among the most conserved enzymes known, with one or more isoforms present in all sequenced eukaryotic genomes. PP1 dephosphorylates specific serine/threonine phosphoproteins as defined by...
14.
Kerk D, Moorhead G
BMC Evol Biol
. 2010 Jun;
10:196.
PMID: 20576132
Background: Phosphorylated phosphatidylinositol (PtdIns) lipids, produced and modified by PtdIns kinases and phosphatases, are critical to the regulation of diverse cellular functions. The myotubularin PtdIns-phosphate phosphatases have been well characterized...
15.
Douglas P, Zhong J, Ye R, Moorhead G, Xu X, Lees-Miller S
Mol Cell Biol
. 2010 Jan;
30(6):1368-81.
PMID: 20065038
The catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs) plays a major role in the repair of DNA double-strand breaks (DSBs) by nonhomologous end joining (NHEJ). We have previously shown...
16.
Uhrig R, Ng K, Moorhead G
Trends Plant Sci
. 2009 Sep;
14(9):505-11.
PMID: 19720555
PII in prokaryotic organisms is a crucial integrator of cellular carbon, nitrogen and energy levels. In higher plants, however, its role remains significantly less clear. Previous findings suggest that PII-N-acetylglutamate...
17.
Moorhead G, De Wever V, Templeton G, Kerk D
Biochem J
. 2008 Dec;
417(2):401-9.
PMID: 19099538
Protein phosphorylation appears to be a universal mechanism of protein regulation. Genomics has provided the means to compile inventories of protein phosphatases across a wide selection of organisms and this...
18.
Lohmeier-Vogel E, Kerk D, Nimick M, Wrobel S, Vickerman L, Muench D, et al.
BMC Plant Biol
. 2008 Nov;
8:120.
PMID: 19038037
Background: Starch accumulation and degradation in chloroplasts is accomplished by a suite of over 30 enzymes. Recent work has emphasized the importance of multi-protein complexes amongst the metabolic enzymes, and...
19.
Moorhead G, Trinkle-Mulcahy L, Nimick M, De Wever V, Campbell D, Gourlay R, et al.
BMC Biochem
. 2008 Nov;
9:28.
PMID: 19000314
Background: Protein phosphatase one (PP1) is a ubiquitously expressed, highly conserved protein phosphatase that dephosphorylates target protein serine and threonine residues. PP1 is localized to its site of action by...
20.
Kerk D, Templeton G, Moorhead G
Plant Physiol
. 2007 Dec;
146(2):351-67.
PMID: 18156295
In addition to the major serine/threonine-specific phosphoprotein phosphatase, Mg(2+)-dependent phosphoprotein phosphatase, and protein tyrosine phosphatase families, there are novel protein phosphatases, including enzymes with aspartic acid-based catalysis and subfamilies of...