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Graziano Colombo

Explore the profile of Graziano Colombo including associated specialties, affiliations and a list of published articles. Areas
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Articles 62
Citations 1083
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Recent Articles
1.
DellAcqua R, Fagnani F, Wojciechowska M, Marinotto D, Colombo G, Dalle-Donne I, et al.
Dalton Trans . 2025 Jan; 54(8):3314-3322. PMID: 39831467
The synthesis of novel highly phosphorescent N^C^N tridentate platinum(II)-complex-peptide nucleic acid (PNA) bioconjugates was accomplished through the solid-phase approach. Melting temperature measurements and circular dichroism spectroscopy studies demonstrated that these...
2.
Bianchi F, Le Noci V, Bernardo G, Gagliano N, Colombo G, Sommariva M, et al.
PLoS One . 2024 May; 19(5):e0303875. PMID: 38776331
Background: It is amply demonstrated that cigarette smoke (CS) has a high impact on lung tumor progression worsening lung cancer patient prognosis and response to therapies. Alteration of immune cell...
3.
Moschini E, Colombo G, Chirico G, Capitani G, Dalle-Donne I, Mantecca P
Sci Rep . 2023 Feb; 13(1):2326. PMID: 36759527
It is well known that copper oxide nanoparticles (CuO NPs) are heavily toxic on in vitro systems. In human alveolar epithelial cells, the mechanism of toxicity is mostly related to...
4.
Colombo G, Altomare A, Astori E, Landoni L, Garavaglia M, Rossi R, et al.
Int J Mol Sci . 2023 Jan; 24(1). PMID: 36614132
Urea is the uremic toxin accumulating with the highest concentration in the plasma of chronic kidney disease (CKD) patients, not being completely cleared by dialysis. Urea accumulation is reported to...
5.
Colombo G, Astori E, Landoni L, Garavaglia M, Altomare A, Lionetti M, et al.
J Appl Toxicol . 2022 Jul; 42(12):1948-1961. PMID: 35854198
Indoxyl sulphate (IS) is a uremic toxin accumulating in the plasma of chronic kidney disease (CKD) patients. IS accumulation induces side effects in the kidneys, bones and cardiovascular system. Most...
6.
Garavaglia M, Giustarini D, Colombo G, Reggiani F, Finazzi S, Calatroni M, et al.
Int J Mol Sci . 2022 Mar; 23(5). PMID: 35269995
Thiols (sulfhydryl groups) are effective antioxidants that can preserve the correct structure of proteins, and can protect cells and tissues from damage induced by oxidative stress. Abnormal levels of thiols...
7.
Reggiani F, Colombo G, Astori E, Landoni L, Finazzi S, Milzani A, et al.
Int Urol Nephrol . 2021 Sep; 54(5):1145-1153. PMID: 34510284
Purpose: Iron is usually administered in hemodialysis patients by parenteral route, as oral absorption is poor due to high hepcidin levels. However, administrations of intravenous iron and iron overload are...
8.
Astori E, Garavaglia M, Colombo G, Landoni L, Portinaro N, Milzani A, et al.
Nutr Res Rev . 2021 Apr; 35(1):70-97. PMID: 33926594
Cigarette smoke (CS) is likely the most common preventable cause of human morbidity and mortality worldwide. Consequently, inexpensive interventional strategies for preventing CS-related diseases would positively impact health systems. Inhaled...
9.
Giustarini D, Dalle-Donne I, Colombo G, Milzani A, Santucci A, Rossi R
Anal Biochem . 2021 Feb; 618:114125. PMID: 33524411
Protein Thiolation Index (PTI) has been recently proposed as a new biomarker of oxidative stress. It is calculated by measuring both free thiols and S-thiolated proteins in plasma with the...
10.
Ruggerone B, Colombo G, Paltrinieri S
Front Vet Sci . 2020 Dec; 7:566402. PMID: 33363227
In people, serum Protein Carbonyls (PCOs) increase during oxidative stress (OS) due to oxidative damage to proteins. OS is often associated with inflammation and especially with sepsis, a condition hard...