Daniela Giustarini
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Explore the profile of Daniela Giustarini including associated specialties, affiliations and a list of published articles.
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104
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Recent Articles
1.
Bottoni L, Minetti A, Realini G, Pio E, Giustarini D, Rossi R, et al.
Oncogene
. 2024 Apr;
43(22):1701-1713.
PMID: 38600165
Triple-negative breast cancer (TNBC) is a very aggressive and heterogeneous group of tumors. In order to develop effective therapeutic strategies, it is therefore essential to identify the subtype-specific molecular mechanisms...
2.
Pan X, Giustarini D, Lang F, Rossi R, Wieder T, Koberle M, et al.
Cell Cycle
. 2023 Jul;
22(17):1827-1853.
PMID: 37522842
Desipramine a representative of tricyclic antidepressants (TCAs) promotes recovery of depressed patients by inhibition of reuptake of neurotransmitters serotonin (SER) and norepinephrine (NE) in the presynaptic membrane by directly blocking...
3.
Giustarini D, Milzani A, Dalle-Donne I, Rossi R
Antioxidants (Basel)
. 2023 May;
12(5).
PMID: 37237960
Glutathione (GSH) has special antioxidant properties due to its high intracellular concentration, ubiquity, and high reactivity towards electrophiles of the sulfhydryl group of its cysteine moiety. In most diseases where...
4.
Colombo G, Altomare A, Astori E, Landoni L, Garavaglia M, Rossi R, et al.
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36614132
Urea is the uremic toxin accumulating with the highest concentration in the plasma of chronic kidney disease (CKD) patients, not being completely cleared by dialysis. Urea accumulation is reported to...
5.
Braconi D, Geminiani M, Psarelli E, Giustarini D, Marzocchi B, Rossi R, et al.
Cells
. 2022 Nov;
11(22).
PMID: 36429096
Nitisinone (NTBC) was recently approved to treat alkaptonuria (AKU), but there is no information on its impact on oxidative stress and inflammation, which are observed in AKU. Therefore, serum samples...
6.
Galli F, Marcantonini G, Giustarini D, Albertini M, Migni A, Zatini L, et al.
Antioxidants (Basel)
. 2022 Jul;
11(7).
PMID: 35883857
SARS-CoV-2 infection can cause a severe respiratory distress syndrome with inflammatory and thrombotic complications, the severity of which increases with patients' age and presence of comorbidity. The reasons for an...
7.
Colombo G, Astori E, Landoni L, Garavaglia M, Altomare A, Lionetti M, et al.
J Appl Toxicol
. 2022 Jul;
42(12):1948-1961.
PMID: 35854198
Indoxyl sulphate (IS) is a uremic toxin accumulating in the plasma of chronic kidney disease (CKD) patients. IS accumulation induces side effects in the kidneys, bones and cardiovascular system. Most...
8.
Bartolini D, Arato I, Mancuso F, Giustarini D, Bellucci C, Vacca C, et al.
J Pineal Res
. 2022 May;
73(1):e12806.
PMID: 35524288
Melatonin (MLT) is a cytoprotective agent holding potential to prevent cadmium (Cd) toxicity and its impact in testicular function and fertility. In this study, we explored such potential in porcine...
9.
Garavaglia M, Giustarini D, Colombo G, Reggiani F, Finazzi S, Calatroni M, et al.
Int J Mol Sci
. 2022 Mar;
23(5).
PMID: 35269995
Thiols (sulfhydryl groups) are effective antioxidants that can preserve the correct structure of proteins, and can protect cells and tissues from damage induced by oxidative stress. Abnormal levels of thiols...
10.
Galderisi S, Milella M, Rossi M, Cicaloni V, Rossi R, Giustarini D, et al.
Arch Biochem Biophys
. 2022 Jan;
717:109137.
PMID: 35090868
Alkaptonuria (AKU) is an ultra-rare genetic disease caused by a deficient activity of the enzyme homogentisate 1,2-dioxygenase (HGD) leading to the accumulation of homogentisic acid (HGA) on connective tissues. Even...