Graham L Jones
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Explore the profile of Graham L Jones including associated specialties, affiliations and a list of published articles.
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34
Citations
542
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Recent Articles
1.
Rodriguez C, Bechek S, Jones G, Nakayama L, Akiyama T, Kim G, et al.
Cell Rep
. 2022 Oct;
41(4):111505.
PMID: 36288715
Gene-based therapeutic strategies to lower ataxin-2 levels are emerging for the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and spinocerebellar ataxia type 2 (SCA2). Additional strategies to lower levels of ataxin-2...
2.
Alghamdi O, King N, Andronicos N, Jones G, Chami B, Witting P, et al.
Amino Acids
. 2022 Apr;
54(7):1001-1011.
PMID: 35386060
Hypertension is a major risk factor for kidney and cardiovascular disease. The treatment of hypertensive individuals by selected ACE inhibitors and certain di-and tripeptides halts the progression of renal deterioration...
3.
Sadgrove N, Padilla-Gonzalez G, Green A, Langat M, Mas-Claret E, Lyddiard D, et al.
Plants (Basel)
. 2021 Apr;
10(4).
PMID: 33923613
Australia's endemic desert shrubs are commonly aromatic, with chemically diverse terpenes and phenylpropanoids in their headspace profiles. Species from the genus (Scrophulariaceae ex. Myoporaceae) are the most common, with 215...
4.
Alghamdi O, King N, Jones G, Moens P
Amino Acids
. 2021 Jan;
53(2):183-193.
PMID: 33404911
Some dipeptides have been implicated in myocardial protection, but little is known about their membrane transporter PEPT2. The aim of this study was to determine whether the expression and activity...
5.
Sadgrove N, Padilla-Gonzalez G, Telford I, Greatrex B, Jones G, Andrew R, et al.
Plants (Basel)
. 2020 Nov;
9(11).
PMID: 33202983
The highly aromatic Australian mint bushes from the genus Labill. produce a high yield of essential oil on hydrodistillation. Together with its rich history, horticultural potential, iconic flowers, and aromatic...
6.
Yu H, Chhabra K, Thompson Z, Jones G, Kiran S, Shangguan G, et al.
Mol Metab
. 2020 Apr;
35:100957.
PMID: 32244188
Objective: The steep rise in the prevalence of obesity and its related metabolic syndrome have become a major worldwide health concerns. Melanocortin peptides from hypothalamic arcuate nucleus (Arc) POMC neurons...
7.
Yu H, Thompson Z, Kiran S, Jones G, Mundada L, Rubinstein M, et al.
J Endocrinol
. 2020 Feb;
245(1):115-127.
PMID: 32027603
Proopiomelanocortin (POMC) neurons in the hypothalamic arcuate nucleus (ARC) are essential for normal energy homeostasis. Maximal ARC Pomc transcription is dependent on neuronal Pomc enhancer 1 (nPE1), located 12 kb...
8.
Jones G, Wittmann G, Yokosawa E, Yu H, Mercer A, Lechan R, et al.
eNeuro
. 2019 Apr;
6(2).
PMID: 30957016
Hypothalamic POMC deficiency leads to obesity and metabolic deficiencies, largely due to the loss of melanocortin peptides. However, POMC neurons in the arcuate nucleus (ARC) are comprised of glutamatergic and...
9.
Sadgrove N, Collins T, Legendre S, Klepp J, Jones G, Greatrex B
Nat Prod Commun
. 2019 Feb;
11(9):1211-1214.
PMID: 30807001
The strongly aromatic Australian desert species Eremophila dalyana is an Aboriginal medicinal plant that continues to be used today in Central Australia in the treatment of respiratory complaints and Sarcoptes...
10.
Tooke B, Yu H, Adams J, Jones G, Sutton-Kennedy T, Mundada L, et al.
Mol Metab
. 2018 Dec;
20:194-204.
PMID: 30503832
Objective: Life-threatening hypoglycemia is a major limiting factor in the management of diabetes. While it is known that counterregulatory responses to hypoglycemia are impaired in diabetes, molecular mechanisms underlying the...