» Authors » Gouqing Ge

Gouqing Ge

Explore the profile of Gouqing Ge including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 185
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Zhang N, Scorsone K, Ge G, Kaffes C, Dobrolecki L, Mukherjee M, et al.
J Biomol Screen . 2014 Feb; 19(6):878-89. PMID: 24525869
Separase is an endopeptidase that cleaves cohesin subunit Rad21, facilitating the repair of DNA damage during interphase and the resolution of sister chromatid cohesion at anaphase. Separase activity is negatively...
2.
Mukherjee M, Ge G, Zhang N, Edwards D, Sumazin P, Sharan S, et al.
Oncogene . 2013 Nov; 33(48):5511-5522. PMID: 24276237
Separase, a protease encoded by the ESPL1 gene, cleaves the chromosomal cohesin during mitosis. Separase protein and transcripts are overexpressed in a wide range of human cancers. To investigate the...
3.
Mukherjee M, Ge G, Zhang N, Huang E, Nakamura L, Minor M, et al.
PLoS One . 2011 Jul; 6(7):e22167. PMID: 21799785
Background: Cohesin protease Separase plays a key role in faithful segregation of sister chromatids by cleaving the cohesin complex at the metaphase to anaphase transition. Homozygous deletion of ESPL1 gene...
4.
Lu X, Lu Y, Zhao Y, Jaeweon K, Kang J, Xiao-Nan L, et al.
Mol Cancer Res . 2008 Jun; 6(6):937-46. PMID: 18567798
Osteosarcoma is a primary malignant tumor of bone arising from primitive bone-forming mesenchymal cells and accounts for approximately 60% of malignant bone tumors. Our comparative genomic hybridization (CGH) studies have...
5.
Pati D, Haddad B, Haegele A, Thompson H, Kittrell F, Shepard A, et al.
Cancer Res . 2004 Aug; 64(16):5608-16. PMID: 15313898
The absence of p53 function increases risk for spontaneous tumorigenesis in the mammary gland. Hormonal stimulation enhances tumor risk in p53-null mammary epithelial cells as well as the incidence of...
6.
Liu Y, Ludes-Meyers J, Zhang Y, Munoz-Medellin D, Kim H, Lu C, et al.
Oncogene . 2002 Oct; 21(50):7680-9. PMID: 12400010
AP-1 transcription factors play a critical role in signal transduction pathways in many cells. We have investigated the role of AP-1 in controlling proliferative signals in breast cells, and have...