Gopal Srivastava
Overview
Explore the profile of Gopal Srivastava including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
39
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0
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Recent Articles
1.
Srivastava G, Brylinski M
Nutrients
. 2025 Feb;
17(3).
PMID: 39940326
The human gut microbiome is critical for host health by facilitating essential metabolic processes. Our study presents a data-driven analysis across 312 bacterial species and 154 unique metabolites to enhance...
2.
Srivastava G, Liu M, Ni X, Pu L, Brylinski M
Methods Mol Biol
. 2024 Nov;
2867:79-104.
PMID: 39576576
The elucidation of protein structure and function plays a pivotal role in understanding biological processes and facilitating drug discovery. With the exponential growth of protein sequence data, machine learning techniques...
3.
Liu M, Srivastava G, Ramanujam J, Brylinski M
Biomolecules
. 2024 Mar;
14(3).
PMID: 38540674
Drug combination therapy shows promise in cancer treatment by addressing drug resistance, reducing toxicity, and enhancing therapeutic efficacy. However, the intricate and dynamic nature of biological systems makes identifying potential...
4.
Liu M, Srivastava G, Ramanujam J, Brylinski M
Sci Rep
. 2024 Jan;
14(1):1668.
PMID: 38238448
Combination therapy has gained popularity in cancer treatment as it enhances the treatment efficacy and overcomes drug resistance. Although machine learning (ML) techniques have become an indispensable tool for discovering...
5.
Liu M, Srivastava G, Ramanujam J, Brylinski M
Res Sq
. 2023 Nov;
PMID: 37961281
Combination therapy has gained popularity in cancer treatment as it enhances the treatment efficacy and overcomes drug resistance. Although machine learning (ML) techniques have become an indispensable tool for discovering...
6.
Singha M, Pu L, Srivastava G, Ni X, Stanfield B, Uche I, et al.
Cancers (Basel)
. 2023 Aug;
15(16).
PMID: 37627077
Deregulated protein kinases are crucial in promoting cancer cell proliferation and driving malignant cell signaling. Although these kinases are essential targets for cancer therapy due to their involvement in cell...
7.
Shi W, Singha M, Pu L, Srivastava G, Ramanujam J, Brylinski M
Biomolecules
. 2022 Aug;
12(8).
PMID: 36008947
The binding of small organic molecules to protein targets is fundamental to a wide array of cellular functions. It is also routinely exploited to develop new therapeutic strategies against a...
8.
Shi W, Singha M, Srivastava G, Pu L, Ramanujam J, Brylinski M
Front Pharmacol
. 2022 Apr;
13:837715.
PMID: 35359869
Computational modeling is an essential component of modern drug discovery. One of its most important applications is to select promising drug candidates for pharmacologically relevant target proteins. Because of continuing...
9.
Gurram S, Srivastava G, Badve V, Nandre V, Gundu S, Doshi P
Appl Biochem Biotechnol
. 2021 Sep;
194(2):827-847.
PMID: 34550501
PEGylation is a reductive alkylation of a protein N-terminal/α-amine of protein with mPEG chain by reducing agent. To obtain quantitative and site-specific PEGylation, sodium cyanoborohydride is commonly used as a...
10.
Walke S, Srivastava G, Routaray C, Dhavale D, Pai K, Doshi J, et al.
Int J Biol Macromol
. 2017 Oct;
107(Pt B):2044-2056.
PMID: 29037872
The paper explained the microencapsulation of three different antigenic materials viz. Diphtheria toxoid (DT), whole cell pertussis antigens (PT and FHA) and tetanus toxoid (TT) by coacervation method using water...