Gonzalo Herradon
Overview
Explore the profile of Gonzalo Herradon including associated specialties, affiliations and a list of published articles.
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76
Citations
711
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Recent Articles
1.
Caneque-Rufo H, Fontan-Baselga T, Galan-Llario M, Zuccaro A, Sanchez-Alonso M, Gramage E, et al.
Neurobiol Dis
. 2024 Dec;
205():106776.
PMID: 39722335
Obesity and metabolic disorders, such as metabolic syndrome (MetS) facilitate the development of neurodegenerative diseases and cognitive decline. Persistent neuroinflammation plays an important role in this process. Pleiotrophin (PTN) is...
2.
Fontan-Baselga T, Caneque-Rufo H, Rivera-Illades E, Gramage E, Zapico J, de Pascual-Teresa B, et al.
Front Pharmacol
. 2024 Dec;
15:1506049.
PMID: 39712494
Alzheimer's disease (AD) is a major neurodegenerative disorder that courses with chronic neuroinflammation. Pleiotrophin (PTN) is an endogenous inhibitor of Receptor Protein Tyrosine Phosphatase (RPTP) β/ζ which is upregulated in...
3.
Galan-Llario M, Rodriguez-Zapata M, Fontan-Baselga T, Caneque-Rufo H, Garcia-Guerra A, Fernandez B, et al.
CNS Neurosci Ther
. 2024 Dec;
30(12):e70159.
PMID: 39654349
Aims: To investigate whether pleiotrophin (PTN) overexpression influences ethanol consumption during adolescence and its effects on glial responses, neurogenesis, and perineuronal nets (PNNs) in the mouse hippocampus. Methods: Male and...
4.
Ballesteros-Pla C, Sevillano J, Sanchez-Alonso M, Limones M, Pita J, Zapateria B, et al.
Int J Mol Sci
. 2024 Oct;
25(20).
PMID: 39456743
Pleiotrophin (PTN) is crucial for embryonic development and pancreas organogenesis as it regulates metainflammation, metabolic homeostasis, thermogenesis, and glucose tolerance. Pleiotrophin deletion is associated with a lipodystrophic phenotype in which...
5.
Rodriguez-Zapata M, Lopez-Rodriguez R, Ramos-Alvarez M, Herradon G, Perez-Garcia C, Gramage E
Toxicology
. 2024 Sep;
509:153947.
PMID: 39255863
The hippocampus is one of the most vulnerable regions affected in disorders characterized by overt neuroinflammation such as neurodegenerative diseases. Pleiotrophin (PTN) is a neurotrophic factor that modulates acute neuroinflammation...
6.
Galan-Llario M, Gramage E, Garcia-Guerra A, Torregrosa A, Gasparyan A, Navarro D, et al.
Neuropharmacology
. 2024 Jan;
247:109850.
PMID: 38295947
Adolescence is a critical period for brain maturation in which this organ undergoes critical plasticity mechanisms that increase its vulnerability to the effects of alcohol. Significantly, ethanol-induced disruption of hippocampal...
7.
Kastana P, Ntenekou D, Mourkogianni E, Enake M, Xanthopoulos A, Choleva E, et al.
Int J Cancer
. 2023 Jun;
153(5):1051-1066.
PMID: 37260355
Protein tyrosine phosphatase receptor zeta 1 (PTPRZ1) is a transmembrane tyrosine phosphatase (TP) expressed in endothelial cells and required for stimulation of cell migration by vascular endothelial growth factor A...
8.
Rodriguez-Zapata M, Galan-Llario M, Caneque-Rufo H, Sevillano J, Sanchez-Alonso M, Zapico J, et al.
Biomedicines
. 2023 May;
11(5).
PMID: 37238989
Binge drinking during adolescence increases the risk of alcohol use disorder, possibly by involving alterations of neuroimmune responses. Pleiotrophin (PTN) is a cytokine that inhibits Receptor Protein Tyrosine Phosphatase (RPTP)...
9.
Costa-Machado L, Garcia-Dominguez E, McIntyre R, Lopez-Aceituno J, Ballesteros-Gonzalez A, Tapia-Gonzalez A, et al.
Nat Commun
. 2023 May;
14(1):2779.
PMID: 37188705
Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show that harmol, a...
10.
Del Campo M, Peeters C, Johnson E, Vermunt L, Hok-A-Hin Y, van Nee M, et al.
Nat Aging
. 2023 Apr;
2(11):1040-1053.
PMID: 37118088
Development of disease-modifying therapies against Alzheimer's disease (AD) requires biomarkers reflecting the diverse pathological pathways specific for AD. We measured 665 proteins in 797 cerebrospinal fluid (CSF) samples from patients...