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Glenn Merlino

Explore the profile of Glenn Merlino including associated specialties, affiliations and a list of published articles. Areas
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Articles 134
Citations 5347
Followers 0
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Recent Articles
21.
Dahut W, Merlino G, Misteli T
Nat Cancer . 2022 Feb; 2(3):247-250. PMID: 35121961
No abstract available.
22.
Spencer C, McQuade J, Gopalakrishnan V, McCulloch J, Vetizou M, Cogdill A, et al.
Science . 2021 Dec; 374(6575):1632-1640. PMID: 34941392
Gut bacteria modulate the response to immune checkpoint blockade (ICB) treatment in cancer, but the effect of diet and supplements on this interaction is not well studied. We assessed fecal...
23.
Valencia J, Erwin-Cohen R, Clavijo P, Allen C, Sanford M, Day C, et al.
Cancer Res . 2021 Oct; 81(23):5977-5990. PMID: 34642183
The relationship between cancer and autoimmunity is complex. However, the incidence of solid tumors such as melanoma has increased significantly among patients with previous or newly diagnosed systemic autoimmune disease...
24.
Leonard M, Puts G, Pamidimukkala N, Adhikary G, Xu Y, Kwok E, et al.
Oncogene . 2021 Oct; 40(45):6394. PMID: 34635800
No abstract available.
25.
Leonard M, Puts G, Pamidimukkala N, Adhikary G, Xu Y, Kwok E, et al.
Oncogene . 2021 Aug; 40(45):6329-6342. PMID: 34433909
Hepatocyte growth factor-overexpressing mice that harbor a deletion of the Ink4a/p16 locus (HP mice) form melanomas with low metastatic potential in response to UV irradiation. Here we report that these...
26.
Paradis J, Acosta M, Saddawi-Konefka R, Kishore A, Lubrano S, Gomes F, et al.
Clin Cancer Res . 2021 Aug; 27(16):4664. PMID: 34389658
No abstract available.
27.
Xu M, Mehl L, Zhang T, Thakur R, Sowards H, Myers T, et al.
Am J Hum Genet . 2021 Aug; 108(9):1611-1630. PMID: 34343493
Genome-wide association studies (GWASs) have identified a melanoma-associated locus on chromosome band 7p21.1 with rs117132860 as the lead SNP and a secondary independent signal marked by rs73069846. rs117132860 is also...
28.
Qin Y, Zuo Q, Huang L, Huang L, Merlino G, Yu Y
NPJ Precis Oncol . 2021 Jul; 5(1):68. PMID: 34282258
Targeting mutant BRAF in patients with melanomas harboring this oncogene has been highly successful as a first-line treatment, but other mutations may affect its efficacy and alter the route of...
29.
El Meskini R, Atkinson D, Kulaga A, Abdelmaksoud A, Gumprecht M, Pate N, et al.
Mol Cancer Res . 2021 Apr; 19(8):1422-1436. PMID: 33888600
Only a subset of patients responds to immune checkpoint blockade (ICB) in melanoma. A preclinical model recapitulating the clinical activity of ICB would provide a valuable platform for mechanistic studies....
30.
Paradis J, Acosta M, Saddawi-Konefka R, Kishore A, Gomes F, Arang N, et al.
Clin Cancer Res . 2021 Feb; 27(11):3190-3200. PMID: 33568347
Purpose: Uveal melanoma is the most common eye cancer in adults. Approximately 50% of patients with uveal melanoma develop metastatic uveal melanoma (mUM) in the liver, even after successful treatment...