Giuseppe dOrazio
Overview
Explore the profile of Giuseppe dOrazio including associated specialties, affiliations and a list of published articles.
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11
Citations
83
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Recent Articles
1.
Fernandez Alarcon J, Perez Schmidt P, Panini N, Caruso F, Violatto M, Sukubo N, et al.
Adv Sci (Weinh)
. 2025 Feb;
:e2407458.
PMID: 39950558
Macrophages are crucial drivers of innate immunity. Reprogramming macrophages to a restorative phenotype in cancer or autoimmune diseases can stop their cancer-promoting activity or trigger anti-inflammatory immunity. Glycans have emerged...
2.
dOrazio G, Ragone R, Rizzuti A, Abatematteo F, Ciampa A, Ghisa G, et al.
ChemistryOpen
. 2024 Dec;
:e202400259.
PMID: 39659060
Many industrial processes use aromatic hydrocarbons as solvents, including benzene, toluene, ethylbenzene, and xylene (BTEX). However, their use is discouraged due to their toxicological profile. Research is ongoing to find...
3.
dOrazio G, La Ferla B
Molecules
. 2024 Nov;
29(21).
PMID: 39519708
Sodium-glucose co-transporter 1 (SGLT1) is primarily expressed on the membrane of enterocytes, a type of epithelial cell found in the intestines, where it mediates the unidirectional absorption of glucose and...
4.
Kohout C, Del Bino L, Petrosilli L, dOrazio G, Romano M, Codee J, et al.
Chemistry
. 2024 Jun;
30(47):e202401695.
PMID: 38889267
Glycoconjugate vaccines are based on chemical conjugation of pathogen-associated carbohydrates with immunogenic carrier proteins and are considered a very cost-effective way to prevent infections. Most of the licensed glycoconjugate vaccines...
5.
La Ferla B, dOrazio G
Curr Org Synth
. 2020 Sep;
18(1):3-22.
PMID: 32972347
Background: Pyranoid spirofused sugar derivatives represent a class of compounds with a significant impact in the literature. From the structural point of view, the rigidity inferred by the spirofused entity...
6.
Ricciardiello F, Votta G, Palorini R, Raccagni I, Brunelli L, Paiotta A, et al.
Cell Death Dis
. 2018 Mar;
9(3):377.
PMID: 29515119
Cancer aberrant N- and O-linked protein glycosylation, frequently resulting from an augmented flux through the Hexosamine Biosynthetic Pathway (HBP), play different roles in tumor progression. However, the low specificity and...
7.
Airoldi C, dOrazio G, Richichi B, Guzzi C, Baldoneschi V, Colombo L, et al.
Chem Asian J
. 2015 Nov;
11(2):299-309.
PMID: 26522445
A small library of glycofused tricyclic compounds with a central pyran ring chemically modified in the position para to the ring oxygen has been synthesised. The influence of the chemical...
8.
Airoldi C, Mourtas S, Cardona F, Zona C, Sironi E, dOrazio G, et al.
Eur J Med Chem
. 2014 Jul;
85:43-50.
PMID: 25072875
Nanoliposomes decorated on their surface with ligands for Aβ-peptides, the key morphological features of Alzheimer's disease (AD), have been synthesized and characterized for their ability to target Aβ-peptide aggregates. A...
9.
Cardani D, Sardi C, La Ferla B, dOrazio G, Sommariva M, Marcucci F, et al.
Mol Cancer
. 2014 Feb;
13:23.
PMID: 24495286
Background: Recent studies demonstrated that engagement of sodium glucose transporter 1 (SGLT-1) by orally administered D-glucose protects the intestinal mucosa from lipopolysaccharide (LPS)-induced injury. We tested whether SGLT-1 engagement might...
10.
Sassi M, Mascheroni L, Ruffo R, Salamone M, Pagani G, Mari C, et al.
Org Lett
. 2013 Jun;
15(14):3502-5.
PMID: 23795958
A new versatile thiophene derivative exomethylene-3,4-ethylenedioxythiophene (emEDOT) is introduced. The molecule can be straightforwardly prepared in two steps from commercially available derivatives and enables facile further derivatization through both acid...