Giridhara R Jayandharan
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Explore the profile of Giridhara R Jayandharan including associated specialties, affiliations and a list of published articles.
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59
Citations
1273
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Recent Articles
1.
Pathak S, Singh V, Kumar G N, Jayandharan G
Cancer Gene Ther
. 2024 Oct;
31(12):1796-1803.
PMID: 39385010
Advanced-stage hepatocellular carcinoma (HCC) remains an untreatable disease with an overall survival of less than one year. One of the critical molecular mediators contributing to increased resistance to therapy and...
2.
Singh V, Pathak S, Kumar N, Jayandharan G
ACS Omega
. 2024 Jul;
9(28):30945-30953.
PMID: 39035883
Suicide gene therapy is a promising strategy for the potential treatment of hepatocellular carcinoma (HCC). However, the lack of high transduction efficiency and targeted vectors in delivering the suicide genes...
3.
Sarangi P, Senthilkumar M, Amit S, Kumar N, Jayandharan G
J Cell Mol Med
. 2024 Jun;
28(11):e18460.
PMID: 38864710
Haemophilic arthropathy (HA), a common comorbidity in haemophilic patients leads to joint pain, deformity and reduced quality of life. We have recently demonstrated that a long non-coding RNA, Neat1 as...
4.
Sarangi P, Kumar N, Sambasivan R, Ramalingam S, Amit S, Chandra D, et al.
Thromb Res
. 2024 May;
238:151-160.
PMID: 38718473
It is crucial to develop a long-term therapy that targets hemophilia A and B, including inhibitor-positive patients. We have developed an Adeno-associated virus (AAV) based strategy to integrate the bypass...
5.
Maddileti S, Mahato S, Agrawal T, Dave V, Naik M, Ali M, et al.
Stem Cell Res
. 2024 Apr;
77:103413.
PMID: 38631180
Leber Congenital Amaurosis 2 is an early onset retinal dystrophy that occurs due to mutation in RPE65 gene. Here, we report the generation of two patient specific induced pluripotent stem...
6.
Pathak S, Singh V, Kumar N, Jayandharan G
Mol Ther Methods Clin Dev
. 2023 Dec;
31:101166.
PMID: 38149057
Breast carcinoma has one of the highest incidence rates (11.7%), with significant clinical heterogeneity. Although conventional chemotherapy and surgical resection are the current standard of care, the resistance and recurrence,...
7.
Senthilkumar M, Sarangi P, Amit S, Senguttuvan S, Kumar N, Jayandharan G
Thromb Res
. 2023 Sep;
231:8-16.
PMID: 37741049
Hemophilic arthropathy (HA) due to repeated bleeding into the joint cavity is a major cause of morbidity in patients with hemophilia. The molecular mechanisms contributing to this condition are not...
8.
Sarangi P, Senthilkumar M, Kumar N, Senguttuvan S, Vasudevan M, Jayandharan G
J Cell Mol Med
. 2023 May;
27(12):1745-1749.
PMID: 37183540
No abstract available.
9.
Pathak S, Sarangi P, Jayandharan G
Cell Rep Med
. 2022 May;
3(5):100641.
PMID: 35584635
A major cause of infertility in women is impaired ovulation or oogenesis. In this issue of Cell Reports Medicine, Kanatsu-Shinohara et al. demonstrate the potential of gene delivery with adeno-associated...
10.
Maurya S, Sarangi P, Jayandharan G
Cancer Gene Ther
. 2022 Jan;
29(10):1305-1306.
PMID: 35027711
No abstract available.