Gene Therapy for Female Infertility: A Farfetched Dream or Reality?
Overview
General Medicine
Affiliations
A major cause of infertility in women is impaired ovulation or oogenesis. In this issue of Cell Reports Medicine, Kanatsu-Shinohara et al. demonstrate the potential of gene delivery with adeno-associated virus that can cross the blood-follicle barrier and restore oogenesis in congenitally infertile mice.
Abazarikia A, Luan Y, So W, Becker M, Panda S, Swenson S Endocrinology. 2025; 166(4).
PMID: 39888387 PMC: 11890401. DOI: 10.1210/endocr/bqaf022.
Nanomedicine for Maternal and Fetal Health.
Carter D, Better M, Abbasi S, Zulfiqar F, Shapiro R, Ensign L Small. 2023; 20(41):e2303682.
PMID: 37817368 PMC: 11004090. DOI: 10.1002/smll.202303682.