Giovanni Nigita
Overview
Explore the profile of Giovanni Nigita including associated specialties, affiliations and a list of published articles.
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Articles
69
Citations
1344
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Recent Articles
1.
de Faria F, Khurshid S, Sarchet P, Tahara S, Casadei L, Grignol V, et al.
Int J Mol Sci
. 2025 Jan;
25(24.
PMID: 39769278
Retroperitoneal liposarcoma (RPLPS) is one of the most common histologic subtypes of soft tissue sarcoma (STS). Complete surgical resection remains the mainstay treatment, while the high rate of locoregional recurrence...
2.
Marceca G, Romano G, Acunzo M, Nigita G
Methods Mol Biol
. 2024 Dec;
2883:455-495.
PMID: 39702721
Non-coding RNAs (ncRNAs) play crucial roles in gene expression regulation, translation, and disease development, including cancer. They are classified by size in short and long non-coding RNAs. This chapter focuses...
3.
Del Valle-Morales D, Romano G, Nigita G, Saviana M, La Ferlita A, Le P, et al.
Sci Rep
. 2024 Nov;
14(1):27720.
PMID: 39532922
The 5' cap, catalyzed by RNA guanylyltransferase and 5'-phosphatase (RNGTT), is a vital mRNA modification for the functionality of mRNAs. mRNA capping occurs in the nucleus for the maturation of...
4.
Anastas V, Chavdoula E, La Ferlita A, Soysal B, Cosentini I, Nigita G, et al.
bioRxiv
. 2024 Jun;
PMID: 38826406
KDM2B is a JmjC domain lysine demethylase, which promotes cell immortalization, stem cell self-renewal and tumorigenesis. Here we employed a multi-omics strategy to address its role in ribosome biogenesis and...
5.
Calore F, Casadei L, Sarchet P, Fadda P, Nigita G, Coombes K, et al.
Ann Surg
. 2024 May;
PMID: 38771951
Objective: We aimed to assess the levels of MDM2-DNA within extracellular vesicles (EVs) isolated from the serum of retroperitoneal liposarcoma (RLS) patients versus healthy donors, as well as within the...
6.
Tomasello L, Holub S, Nigita G, Distefano R, Croce C
Signal Transduct Target Ther
. 2024 Apr;
9(1):90.
PMID: 38616203
No abstract available.
7.
Liguoro D, Frigerio R, Ortolano A, Sacconi A, Acunzo M, Romano G, et al.
Cell Death Dis
. 2024 Mar;
15(3):208.
PMID: 38472212
Therapy of melanoma has improved dramatically over the last years thanks to the development of targeted therapies (MAPKi) and immunotherapies. However, drug resistance continues to limit the efficacy of these...
8.
Rampioni Vinciguerra G, Capece M, Reggiani Bonetti L, Nigita G, Calore F, Rentsch S, et al.
Signal Transduct Target Ther
. 2024 Feb;
9(1):31.
PMID: 38342897
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease, characterized by an intense desmoplastic reaction that compresses blood vessels and limits nutrient supplies. PDAC aggressiveness largely relies on its extraordinary capability...
9.
La Ferlita A, Alaimo S, Nigita G, Distefano R, Beane J, Tsichlis P, et al.
iScience
. 2024 Feb;
27(2):108810.
PMID: 38303722
tRNA-derived ncRNAs are a heterogeneous class of non-coding RNAs recently proposed to be active regulators of gene expression and be involved in many diseases, including cancer. Consequently, several online resources...
10.
Del Valle-Morales D, Romano G, Le P, Saviana M, Brown R, Micalo L, et al.
bioRxiv
. 2023 Dec;
PMID: 38045284
The 5' cap, catalyzed by RNA guanylyltransferase and 5'-phosphatase (RNGTT), is a vital mRNA modification for the functionality of mRNAs. mRNA capping occurs in the nucleus for the maturation of...