Gilbert W Moeckel
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Explore the profile of Gilbert W Moeckel including associated specialties, affiliations and a list of published articles.
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59
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1910
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Recent Articles
1.
Guo X, Blanc V, Davidson N, Velazquez H, Chen T, Moledina D, et al.
Sci Rep
. 2023 Dec;
13(1):22255.
PMID: 38097707
Cisplatin (CP) induces acute kidney injury (AKI) whereby proximal tubules undergo regulated necrosis. Repair is almost complete after a single dose. We now demonstrate a role for Apolipoprotein B mRNA...
2.
Menon R, Otto E, Barisoni L, Ferreira R, Limonte C, Godfrey B, et al.
medRxiv
. 2023 Jul;
PMID: 37398386
Arteriolar hyalinosis in kidneys is an independent predictor of cardiovascular disease, the main cause of mortality in chronic kidney disease (CKD). The underlying molecular mechanisms of protein accumulation in the...
3.
Melchinger H, Calderon-Gutierrez F, Obeid W, Xu L, Shaw M, Luciano R, et al.
Clin J Am Soc Nephrol
. 2022 Aug;
17(9):1284-1292.
PMID: 35948365
Background And Objectives: Uromodulin, produced exclusively in the kidney's thick ascending limb, is a biomarker of kidney tubular health. However, the relationship between urine uromodulin and histologic changes in the...
4.
Rehan A, Moeckel G, Perazella M
Kidney360
. 2022 Apr;
3(2):405-406.
PMID: 35373119
No abstract available.
5.
Avigan Z, Singh N, Kliegel J, Weiss M, Moeckel G, Cantley L
Transplant Direct
. 2021 Sep;
7(7):e716.
PMID: 34476295
Background: Delayed graft function (DGF) affects over 25% of deceased donor kidney transplants (DDKTs) and is associated with increased cost, worsened graft outcomes, and mortality. While approaches to preventing DGF...
6.
Ferreira C, Kavanagh D, Oheim R, Zimmerman K, Sturznickel J, Li X, et al.
J Bone Miner Res
. 2021 Jan;
36(5):942-955.
PMID: 33465815
Inactivating mutations in human ecto-nucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) may result in early-onset osteoporosis (EOOP) in haploinsufficiency and autosomal recessive hypophosphatemic rickets (ARHR2) in homozygous deficiency. ARHR2 patients are frequently treated with...
7.
Jdiaa S, Moeckel G, Kfoury H, Medawar W, Abu-Alfa A
Am J Transplant
. 2020 Nov;
21(5):1948-1952.
PMID: 33206467
Collagenofibrotic glomerulopathy (CG) is a rare disease characterized by the deposition of collagen type 3 fibrils in the glomeruli. Patients may have proteinuria, hematuria, and/or renal dysfunction. CG is considered...
8.
Moledina D, Wilson F, Kukova L, Obeid W, Luciano R, Kuperman M, et al.
Nephrol Dial Transplant
. 2020 Oct;
36(10):1851-1858.
PMID: 33125471
Background: We previously demonstrated that urine interleukin (IL)-9 and tumor necrosis factor (TNF)-α can distinguish acute interstitial nephritis (AIN) from other causes of acute kidney injury. Here we evaluated the...
9.
Han X, Vesely M, Yang W, Sanmamed M, Badri T, Alawa J, et al.
Sci Transl Med
. 2019 Dec;
11(522).
PMID: 31826980
Systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE) of the skin are autoimmune diseases characterized by inappropriate immune responses against self-proteins; the key elements that determine disease pathogenesis and...
10.
Singh N, Avigan Z, Kliegel J, Shuch B, Montgomery R, Moeckel G, et al.
JCI Insight
. 2019 Jun;
4(12).
PMID: 31217358
An incomplete understanding of the biology of the human kidney, including the relative abundances of and interactions between intrinsic and immune cells, has long constrained the development of therapies for...