Ghazaleh Ashrafi
Overview
Explore the profile of Ghazaleh Ashrafi including associated specialties, affiliations and a list of published articles.
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20
Citations
1850
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Recent Articles
1.
Tiwari A, Myeong J, Hashemiaghdam A, Stunault M, Zhang H, Niu X, et al.
Sci Adv
. 2024 Nov;
10(46):eadp7423.
PMID: 39546604
Glucose has long been considered the primary fuel source for the brain. However, glucose levels fluctuate in the brain during sleep or circuit activity, posing major metabolic stress. Here, we...
2.
Myeong J, Stunault M, Klyachko V, Ashrafi G
Cell Rep
. 2024 May;
43(5):114218.
PMID: 38758651
Glucose has long been considered a primary energy source for synaptic function. However, it remains unclear to what extent alternative fuels, such as lactate/pyruvate, contribute to powering synaptic transmission. By...
3.
Tiwari A, Myeong J, Hashemiaghdam A, Zhang H, Niu X, Laramie M, et al.
bioRxiv
. 2024 Apr;
PMID: 38562794
Glucose has long been considered the primary fuel source for the brain. However, glucose levels fluctuate in the brain during sleep, intense circuit activity, or dietary restrictions, posing significant metabolic...
4.
LaPak K, Saeidi S, Bok I, Wamsley N, Plutzer I, Bhatt D, et al.
Sci Signal
. 2023 Dec;
16(815):eadi9018.
PMID: 38085818
The nuclear factor erythroid 2-related factor 2 (NRF2) transcription factor activates cytoprotective and metabolic gene expression in response to various electrophilic stressors. Constitutive NRF2 activity promotes cancer progression, whereas decreased...
5.
Tiwari A, Hashemiaghdam A, Laramie M, Maschi D, Haddad T, Stunault M, et al.
J Cell Biol
. 2023 Nov;
223(1).
PMID: 37988067
Neurotransmission is an energetically expensive process that underlies cognition. During intense electrical activity or dietary restrictions, the glucose level in the brain plummets, forcing neurons to utilize alternative fuels. However,...
6.
Myeong J, Stunault M, Klyachko V, Ashrafi G
bioRxiv
. 2023 Nov;
PMID: 37986894
Glucose has long been considered a primary source of energy for synaptic function. However, it remains unclear under what conditions alternative fuels, such as lactate/pyruvate, contribute to powering synaptic transmission....
7.
Tiwari A, Hashemiaghdam A, Laramie M, Maschi D, Haddad T, Stunault M, et al.
bioRxiv
. 2023 Mar;
PMID: 36945567
Highlights: Glucose deprivation drives transcriptional reprogramming of neuronal metabolism via CREB and PGC1α. Glucose or food deprivation trigger the neuronal expression of mitochondrial deacetylase sirtuin 3 (Sirt3) both and ....
8.
Dehkharghanian T, Hashemiaghdam A, Ashrafi G
Neurophotonics
. 2022 Jun;
9(4):041410.
PMID: 35769720
The firefly enzyme luciferase has been used in a wide range of biological assays, including bioluminescence imaging of adenosine triphosphate (ATP). The biosensor Syn-ATP utilizes subcellular targeting of luciferase to...
9.
Harbauer A, Hees J, Wanderoy S, Segura I, Gibbs W, Cheng Y, et al.
Neuron
. 2022 Feb;
110(9):1516-1531.e9.
PMID: 35216662
PTEN-induced kinase 1 (PINK1) is a short-lived protein required for the removal of damaged mitochondria through Parkin translocation and mitophagy. Because the short half-life of PINK1 limits its ability to...
10.
Biowaste- and nature-derived (nano)materials: Biosynthesis, stability and environmental applications
Ashrafi G, Nasrollahzadeh M, Jaleh B, Sajjadi M, Ghafuri H
Adv Colloid Interface Sci
. 2022 Jan;
301:102599.
PMID: 35066374
Due to the environmental pollution issues and the supply of drinking/clean water, removal of both inorganic and organic (particularly dyes, nitroarenes, and heavy metals) to non-dangerous products and useful compounds...