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Ghaneya Sayed Hassan

Explore the profile of Ghaneya Sayed Hassan including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 71
Followers 0
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Recent Articles
1.
Hassan G, Rahman D, Abdel Saleh D, Abdel Jaleel G
Chem Pharm Bull (Tokyo) . 2014 Dec; 62(12):1238-51. PMID: 25450632
The benzofuran-morpholinomethyl-pyrazoline hybrids 4a-e, 5a-e and 6a-j were synthesized via reaction of α,β-unsaturated carbonyl compounds 3a-e with hydrazine hydrate, semicarbazide or thiosemicarbazide. Applying the Mannich reaction to 5-(5-aryl-4,5-dihydro-1H-pyrazol-3-yl)-4-methoxybenzofuran-6-ols 7a-e with...
2.
Hassan G, Abou-Seri S, Kamel G, Ali M
Eur J Med Chem . 2014 Mar; 76:482-93. PMID: 24607877
Novel series of celecoxib analogs endowed with benzofuran moiety 3a-e and 9a-d were synthesized and evaluated for COX-1/COX-2 inhibitory activity in vitro. The most potent and selective COX-2 inhibitors -...
3.
Hassan G, Abdel Rahman D
Chem Pharm Bull (Tokyo) . 2013 Feb; 61(2):212-21. PMID: 23370196
New series of substituted glutamine 5a-l and glutamic acid diamides, diureide and dihydrazide 7a-e were synthesized from parent glutamic acid compound 3 and evaluated for their cytotoxic activity against tumor...
4.
Ragab F, Eid N, Hassan G, Nissan Y
Chem Pharm Bull (Tokyo) . 2012 Jan; 60(1):110-20. PMID: 22223382
New series of furosalicylic acids 3a-c, furosalicylanilides 6a-n, furobenzoxazines 8a-f, 1-benzofuran-3-arylprop-2-en-1-ones 12a,b, 6-(aryl-3-oxoprop-1-enyl)-4H-chromen-4-ones 16a-c and 6-[6-aryl-2-thioxo-2,5-dihydropyrimidin-4-yl]-4H-chromen-4-ones 17a-c were synthesized. Anti-inflammatory activity evaluation was performed using carrageenan-induced paw edema model in...
5.
Hassan G, Kadry H, Abou-Seri S, Ali M, Mahmoud A
Bioorg Med Chem . 2011 Oct; 19(22):6808-17. PMID: 22000322
New series of pyrazolo[3,4-d]pyrimidines (7a-e and 13a-d) and pyrazole hydrazones 17a-d were synthesized and evaluated for their antiproliferative activity against human breast adenocarcinoma MCF-7 cell line. Most of the tested...
6.
Abou-Seri S, Farag N, Hassan G
Chem Pharm Bull (Tokyo) . 2011 Sep; 59(9):1124-32. PMID: 21881256
Several hybrid molecules of diphenylamine-2,4'-dicarboxamide with various azolidinones and related heterocyclic rings have been synthesized and explored as epidermal growth factor receptor (EGFR) kinase inhibitors. Most of them displayed promising...
7.
Ragab F, Hassan G, Abu Yossef H, Yahya T, Abd El-Latif H
Arzneimittelforschung . 2010 May; 60(4):171-6. PMID: 20486465
Several thiosemicarbazones (7 and 8), 1,3-thiazolidin-4-ones (9, 10, 13, 14) and 2-thioxo-1,3-imidazolidin-4-ones (11) have been prepared starting from 8-bromo-7-hydroxy-5-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-carbaldehyde (3) and its 4-thio analogue (4). The anticonvulsant activity of all...
8.
Hassan G, Hegazy G, Safwat H
Arch Pharm (Weinheim) . 2006 Jul; 339(8):448-55. PMID: 16832819
The synthesis of new furo-salicylanilides and their heterocyclic derivatives is described. Twenty-three compounds were screened for their molluscicidal activity against Biomphalaria alexandrina snails, the intermediate host of Schistosoma mansoni. Five...
9.
Abadi A, Eissa A, Hassan G
Chem Pharm Bull (Tokyo) . 2003 Jul; 51(7):838-44. PMID: 12843591
Several 1,3,4-trisubstituted pyrazole derivatives were synthesized and screened for their cytotoxic effect in a primary 3 tumor cell line test at 10(-4) M drug concentration. Compounds 19 and 20 reduced...