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Gert Van Isterdael

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Recent Articles
1.
Yang B, Piedfort O, Sanchez-Sanchez G, Lavergne A, Gong M, Peng G, et al.
Sci Immunol . 2025 Feb; 10(104):eadk4841. PMID: 39919198
Parasitic helminths induce the production of interleukin-4 (IL-4), which causes the expansion of virtual memory CD8 T cells (T cells), a cell subset that contributes to the control of coinfection...
2.
Asosingh K, Bayiyana A, Black M, Chakraborty U, Clemente M, Graham A, et al.
Cytometry A . 2024 Aug; 105(9):704-712. PMID: 39095958
This "Best Practices in User Consultation" article is the result of a 2022 International Society for the Advancement of Cytometry (ISAC) membership survey that collected valuable insights from the shared...
3.
Bosteels V, Van Duyse J, Ruyssinck E, Van der Borght K, Nguyen L, Gavel J, et al.
Cytometry A . 2024 Mar; 105(6):464-473. PMID: 38456613
Over the past decade, the flow cytometry field has witnessed significant advancements in the number of fluorochromes that can be detected. This enables researchers to analyze more than 40 markers...
4.
Belkina A, Roe C, Tang V, Back J, Bispo C, Conway A, et al.
Cytometry A . 2023 Nov; 105(2):88-111. PMID: 37941128
The purpose of this document is to provide guidance for establishing and maintaining growth and development of flow cytometry shared resource laboratories. While the best practices offered in this manuscript...
5.
Tulkens D, Boelens M, Naert T, Carron M, Demuynck S, Dewaele S, et al.
Leukemia . 2023 Oct; 37(12):2404-2413. PMID: 37794102
CRISPR-mediated simultaneous targeting of candidate tumor suppressor genes in Xenopus tropicalis allows fast functional assessment of co-driver genes for various solid tumors. Genotyping of tumors that emerge in the mosaic...
6.
Deprez J, Verbeke R, Meulewaeter S, Aernout I, Dewitte H, Decruy T, et al.
Nat Nanotechnol . 2023 Jul; 18(11):1341-1350. PMID: 37430039
The therapeutic potential of liposomes to deliver drugs into inflamed tissue is well documented. Liposomes are believed to largely transport drugs into inflamed joints by selective extravasation through endothelial gaps...
7.
Nguyen T, Thiers L, Van Moerkercke A, Bai Y, Fernandez-Calvo P, Minne M, et al.
Nat Plants . 2023 May; 9(6):926-937. PMID: 37188853
Plant specialized metabolites modulate developmental and ecological functions and comprise many therapeutic and other high-value compounds. However, the mechanisms determining their cell-specific expression remain unknown. Here we describe the transcriptional...
8.
Bosteels V, Marechal S, De Nolf C, Rennen S, Maelfait J, Tavernier S, et al.
Sci Immunol . 2023 May; 8(83):eadd3955. PMID: 37172103
Dendritic cells (DCs) mature in an immunogenic or tolerogenic manner depending on the context in which an antigen is perceived, preserving the balance between immunity and tolerance. Whereas the pathways...
9.
Adriaenssens E, Asselbergh B, Rivera-Mejias P, Bervoets S, Vendredy L, De Winter V, et al.
Nat Cell Biol . 2023 Jan; 25(3):467-480. PMID: 36690850
Mitochondria are complex organelles with different compartments, each harbouring their own protein quality control factors. While chaperones of the mitochondrial matrix are well characterized, it is poorly understood which chaperones...
10.
Gaillochet C, Pena Fernandez A, Goossens V, DHalluin K, Drozdzecki A, Shafie M, et al.
Genome Biol . 2023 Jan; 24(1):6. PMID: 36639800
Background: Testing an ever-increasing number of CRISPR components is challenging when developing new genome engineering tools. Plant biotechnology has few high-throughput options to perform iterative design-build-test-learn cycles of gene-editing reagents....