Gert Jan Fleuren
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Explore the profile of Gert Jan Fleuren including associated specialties, affiliations and a list of published articles.
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71
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2950
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Recent Articles
1.
Schrevel M, Osse E, Prins F, Trimbos J, Fleuren G, Gorter A, et al.
Int J Oncol
. 2017 May;
50(6):1947-1954.
PMID: 28498437
In cervical cancer, the epidermal growth factor receptor (EGFR) is overexpressed in 70-90% of the cases and has been associated with poor prognosis. EGFR-based therapy is currently being explored in...
2.
Mehta A, Osse M, Kolkman-Uljee S, Fleuren G, Jordanova E
Anal Cell Pathol (Amst)
. 2015 Jul;
2015:367837.
PMID: 26146606
The antigen processing machinery (APM) plays an important role in immune recognition of virally infected and transformed cells. Defective expression of the APM component ERAP1 is associated with progression and...
3.
Punt S, Langenhoff J, Putter H, Fleuren G, Gorter A, Jordanova E
Oncoimmunology
. 2015 May;
4(2):e984547.
PMID: 25949881
Both IL-17 and Th17 cells have been ascribed tumor promoting as well as tumor suppressing functions. We reviewed the literature on correlations between IL-17 versus Th17 cells and survival in...
4.
Punt S, Fleuren G, Kritikou E, Lubberts E, Trimbos J, Jordanova E, et al.
Oncoimmunology
. 2015 May;
4(1):e984539.
PMID: 25949866
The role of interleukin (IL)-17 in cancer remains controversial. In view of the growing interest in the targeting of IL-17, knowing its cellular sources and clinical implications is crucial. In...
5.
Punt S, Houwing-Duistermaat J, Schulkens I, Thijssen V, Osse E, de Kroon C, et al.
Mol Cancer
. 2015 Apr;
14:71.
PMID: 25889974
Background: The tumour microenvironment comprises a network of immune response and vascularization factors. From this network, we identified immunological and vascularization gene expression clusters and the correlations between the clusters....
6.
Punt S, van Vliet M, Spaans V, de Kroon C, Fleuren G, Gorter A, et al.
Cancer Immunol Immunother
. 2015 Mar;
64(6):745-53.
PMID: 25795131
Cervical adenocarcinoma comprises approximately 15 % of cervical cancer cases. This histological subtype has different characteristics than cervical squamous cell carcinoma, which may influence disease progression. To study whether the...
7.
Crobach S, Ruano D, van Eijk R, Fleuren G, Minderhout I, Snowdowne R, et al.
J Mol Diagn
. 2014 Dec;
17(2):193-200.
PMID: 25545608
Differentiating primary endometrioid or mucinous ovarian tumors from secondary ovarian tumors can be challenging. We compared somatic mutation profiles of primary and secondary ovarian cancers to investigate if these profiles...
8.
Hoekman E, Smit V, Fleming T, Louwe L, Fleuren G, Hilders C
Fertil Steril
. 2014 Dec;
103(2):469-77.
PMID: 25497447
Objective: To exclude minimal residual disease in remaining ovarian tissue after harvesting the ovarian cortex for cryopreservation, by means of a tailor-made approach. Design: Retrospective case series. Setting: Hospital laboratory....
9.
van Esch E, van Poelgeest M, Kouwenberg S, Osse E, Trimbos J, Fleuren G, et al.
Int J Cancer
. 2014 Sep;
136(4):E95-106.
PMID: 25220367
Human papillomavirus-induced usual-type vulvar intraepithelial neoplasia (uVIN) are infiltrated by immune cells but apparently not cleared. A potential explanation for this is an impaired T cell effector function by an...
10.
van Esch E, van Poelgeest M, Trimbos J, Fleuren G, Jordanova E, van der Burg S
Int J Cancer
. 2014 Sep;
136(4):E85-94.
PMID: 25220265
Human papilloma virus (HPV)-induced usual-type vulvar intraepithelial neoplasia (uVIN) is infiltrated by myeloid cells but the type and role of these cells is unclear. We used triple immunofluorescent confocal microscopy...