Gerrit Erdmann
Overview
Explore the profile of Gerrit Erdmann including associated specialties, affiliations and a list of published articles.
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19
Citations
721
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Recent Articles
1.
Bamberg L, Heigwer F, Wandmacher A, Singh A, Betge J, Rindtorff N, et al.
Int J Cancer
. 2022 Jun;
151(9):1586-1601.
PMID: 35666536
Epigenetic dysregulation is an important feature of colorectal cancer (CRC). Combining epigenetic drugs with other antineoplastic agents is a promising treatment strategy for advanced cancers. Here, we exploited the concept...
2.
Baumann D, Drebant J, Hagele T, Burger L, Serger C, Lauenstein C, et al.
J Immunother Cancer
. 2021 Jul;
9(7).
PMID: 34285105
M2 macrophages promote tumor progression and therapy resistance, whereas proimmunogenic M1 macrophages can contribute to the efficacy of cytostatic and immunotherapeutic strategies. The abundance of M2 macrophages in the immune...
3.
Pogatzki-Zahn E, Gomez-Varela D, Erdmann G, Kaschube K, Segelcke D, Schmidt M
Pain
. 2021 Jan;
162(7):2070-2086.
PMID: 33492035
After surgery, acute pain is still managed insufficiently and may lead to short-term and long-term complications including chronic postsurgical pain and an increased prescription of opioids. Thus, identifying new targets...
4.
Bockmayr T, Erdmann G, Treue D, Jurmeister P, Schneider J, Arndt A, et al.
Lab Invest
. 2020 Jul;
100(10):1288-1299.
PMID: 32601356
Histomorphology and immunohistochemistry are the most common ways of cancer classification in routine cancer diagnostics, but often reach their limits in determining the organ origin in metastasis. These cancers of...
5.
Jevtic M, Lowa A, Novackova A, Kovacik A, Kaessmeyer S, Erdmann G, et al.
Biochim Biophys Acta Mol Cell Res
. 2020 Apr;
1867(8):118722.
PMID: 32302667
Dermal fibroblasts seem critical for epidermal maturation and differentiation and recent work demonstrated that diseased fibroblasts may drive pathophysiological processes. Nevertheless, still very little is known about the actual crosstalk...
6.
Zhan T, Ambrosi G, Wandmacher A, Rauscher B, Betge J, Rindtorff N, et al.
Nat Commun
. 2019 May;
10(1):2197.
PMID: 31097693
In colorectal cancer (CRC), aberrant Wnt signalling is essential for tumorigenesis and maintenance of cancer stem cells. However, how other oncogenic pathways converge on Wnt signalling to modulate stem cell...
7.
Laner-Plamberger S, Oeller M, Poupardin R, Krisch L, Hochmann S, Kalathur R, et al.
Sci Rep
. 2019 May;
9(1):7258.
PMID: 31076619
Pooled human platelet lysate (pHPL) is increasingly used as replacement of animal serum for manufacturing of stromal cell therapeutics. Porcine heparin is commonly applied to avoid clotting of pHPL-supplemented medium...
8.
Schumacher D, Andrieux G, Boehnke K, Keil M, Silvestri A, Silvestrov M, et al.
PLoS Genet
. 2019 Mar;
15(3):e1008076.
PMID: 30925167
Organoid cultures derived from colorectal cancer (CRC) samples are increasingly used as preclinical models for studying tumor biology and the effects of targeted therapies under conditions capturing in vitro the...
9.
Menck K, Sonmezer C, Worst T, Schulz M, Dihazi G, Streit F, et al.
J Extracell Vesicles
. 2017 Nov;
6(1):1378056.
PMID: 29184623
Extracellular vesicles (EVs) are membrane particles secreted from cells into all body fluids. Several EV populations exist differing in size and cellular origin. Using differential centrifugation EVs pelleting at 14,000 ...
10.
Augustin I, Dewi D, Hundshammer J, Erdmann G, Kerr G, Boutros M
Sci Signal
. 2017 Jan;
10(461).
PMID: 28074006
Wnt signaling plays an important role in the self-renewal and differentiation of stem cells. The secretion of Wnt ligands requires Evi (also known as Wls). Genetically ablating Evi provides an...