Gerd Kempermann
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Explore the profile of Gerd Kempermann including associated specialties, affiliations and a list of published articles.
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12664
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Recent Articles
11.
Kempermann G, Lopes J, Zocher S, Schilling S, Ehret F, Garthe A, et al.
Neurobiol Dis
. 2022 Nov;
175:105916.
PMID: 36336243
Personalized medicine intensifies interest in experimental paradigms that delineate sources of phenotypic variation. The paradigm of environmental enrichment allows for comparisons among differently housed laboratory rodents to unravel environmental effects...
12.
Bottcher A, Zarucha A, Kobe T, Gaubert M, Hoppner A, Altenstein S, et al.
Front Psychol
. 2022 Sep;
13:945709.
PMID: 36092026
Regular musical activity as a complex multimodal lifestyle activity is proposed to be protective against age-related cognitive decline and Alzheimer's disease. This cross-sectional study investigated the association and interplay between...
13.
Kempermann G
Front Neurosci
. 2022 May;
16:852680.
PMID: 35495058
Adult hippocampal neurogenesis is a unique and exceptional process in the mammalian brain that in a lifelong and activity-dependent way generates new excitatory principal neurons. A comprehensive view on their...
14.
Senko A, Overall R, Silhavy J, Mlejnek P, Malinska H, Huttl M, et al.
PLoS Genet
. 2022 Apr;
18(4):e1009638.
PMID: 35377872
Neurogenesis in the adult hippocampus contributes to learning and memory in the healthy brain but is dysregulated in metabolic and neurodegenerative diseases. The molecular relationships between neural stem cell activity,...
15.
Kempermann G
Front Psychol
. 2022 Mar;
13:841393.
PMID: 35310213
Evidence-based recommendations for lifestyles to promote healthy cognitive aging (exercise, education, non-smoking, balanced diet, etc.) root in reductionistic studies of mostly physical measurable factors with large effect sizes. In contrast,...
16.
Leiter O, Zhuo Z, Rust R, Wasielewska J, Gronnert L, Kowal S, et al.
Cell Metab
. 2022 Feb;
34(3):408-423.e8.
PMID: 35120590
Although the neurogenesis-enhancing effects of exercise have been extensively studied, the molecular mechanisms underlying this response remain unclear. Here, we propose that this is mediated by the exercise-induced systemic release...
17.
Bernas S, Leiter O, Walker T, Kempermann G
Bio Protoc
. 2021 Oct;
7(21):e2603.
PMID: 34595279
There are two neurogenic niches in the adult mammalian brain: the subventricular zone of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus. Cells from these areas...
18.
Zocher S, Overall R, Berdugo-Vega G, Rund N, Karasinsky A, Adusumilli V, et al.
EMBO J
. 2021 Aug;
40(18):e107100.
PMID: 34337766
Adult neurogenesis enables the life-long addition of functional neurons to the hippocampus and is regulated by both cell-intrinsic molecular programs and behavioral activity. De novo DNA methylation is crucial for...
19.
Berdugo-Vega G, Lee C, Garthe A, Kempermann G, Calegari F
Hippocampus
. 2021 Jun;
31(10):1068-1079.
PMID: 34174010
Adult neurogenesis in the hippocampal dentate gyrus (DG) is an extraordinary form of plasticity fundamental for cognitive flexibility. Recent evidence showed that newborn neurons differentially modulate input to the infra-...
20.
Zocher S, Overall R, Lesche M, Dahl A, Kempermann G
Nat Commun
. 2021 Jun;
12(1):3892.
PMID: 34162876
The decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Lifestyle interventions can improve brain function during aging, but their influence on age-related epigenetic changes...