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Gerben J C Zwezerijnen

Explore the profile of Gerben J C Zwezerijnen including associated specialties, affiliations and a list of published articles. Areas
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Articles 48
Citations 377
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Recent Articles
11.
Boellaard R, Buvat I, Nioche C, Ceriani L, Cottereau A, Guerra L, et al.
J Nucl Med . 2024 Aug; 65(9):1343-1348. PMID: 39089812
Total metabolic tumor volume (TMTV) is prognostic in lymphoma. However, cutoff values for risk stratification vary markedly, according to the tumor delineation method used. We aimed to create a standardized...
12.
Wondergem N, Miedema I, van de Ven R, Zwezerijnen G, de Graaf P, Karagozoglu K, et al.
J Immunother Cancer . 2024 Jul; 12(7). PMID: 39038919
Background: Addition of neoadjuvant immune checkpoint inhibition to standard-of-care interventions for locally advanced oral cancer could improve clinical outcome. Methods: In this study, 16 evaluable patients with stage III/IV oral...
13.
Miedema I, Pouw J, Kwakman A, Zwezerijnen G, Huisman M, Timmer F, et al.
J Immunother Cancer . 2024 Jun; 12(6). PMID: 38886117
Introduction: Immune checkpoint inhibitors (ICIs) can elicit anticancer immune responses, but predictive biomarkers are needed. We measured programmed death ligand 1 (PD-L1) expression in organs and lymph nodes using F-BMS-986192...
14.
Smith C, Yaqub M, Wellenberg R, Knip J, Boellaard R, Zwezerijnen G
EJNMMI Phys . 2024 May; 11(1):45. PMID: 38789880
Purpose: Long axial field-of-view (LAFOV) PET/CT systems enable PET/CT scans with reduced injected activities because of improved sensitivity. With this study, we aimed to examine the foetal radiation dose from...
15.
Wijngaarden J, Jauw Y, Zwezerijnen G, de Wit-van der Veen B, Vugts D, Zijlstra J, et al.
EJNMMI Res . 2024 Feb; 14(1):18. PMID: 38358425
Background: Distribution of mAbs into tumour tissue may occur via different processes contributing differently to the Zr-mAb uptake on PET. Target-specific binding in tumours is of main interest; however, non-specific...
16.
Wijngaarden J, Ahbari A, Pouw J, Greuter H, Bahce I, Zwezerijnen G, et al.
EJNMMI Phys . 2024 Feb; 11(1):16. PMID: 38321232
Background: PET scans using zirconium-89 labelled monoclonal antibodies (Zr-mAbs), known as Zr-immuno-PET, are made to measure uptake in tumour and organ tissue. Uptake is related to the supply of Zr-mAbs...
17.
Pouw J, Hashemi S, Huisman M, Wijngaarden J, Slebe M, Oprea-Lager D, et al.
J Immunother Cancer . 2024 Feb; 12(2). PMID: 38302416
Background: In patients with locally advanced unresectable non-small cell lung cancer (NSCLC), durvalumab, an anti-programmed cell death ligand-1 (PD-L1) antibody, has shown improved overall survival when used as consolidation therapy...
18.
Miedema I, Wijngaarden J, Pouw J, Zwezerijnen G, Sebus H, Smit E, et al.
Cancers (Basel) . 2023 Dec; 15(23). PMID: 38067257
Introduction: Zr-immuno-PET (positron emission tomography with zirconium-89-labeled monoclonal antibodies ([Zr]Zr-mAbs)) can be used to study the biodistribution of mAbs targeting the immune system. The measured uptake consists of target-specific and...
19.
Smith C, Zwezerijnen G, den Hollander M, Weijland J, Yaqub M, Boellaard R
Eur J Nucl Med Mol Imaging . 2023 Nov; 51(4):1070-1078. PMID: 37953391
Purpose: Standardised uptake values (SUV) are commonly used to quantify F-FDG lesion uptake. However, SUVs may suffer from several uncertainties and errors. Long-axial field-of-view (LAFOV) PET/CT systems might enable image-based...
20.
Ferrandez M, Golla S, Eertink J, de Vries B, Wiegers S, Zwezerijnen G, et al.
EJNMMI Res . 2023 Sep; 13(1):88. PMID: 37758869
Background: Convolutional neural networks (CNNs), applied to baseline [F]-FDG PET/CT maximum intensity projections (MIPs), show potential for treatment outcome prediction in diffuse large B-cell lymphoma (DLBCL). The aim of this...