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Gerard Audran

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Articles 53
Citations 130
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Recent Articles
1.
Embo-Ibouanga A, Nguyen M, Paloque L, Joly J, Bikanga R, Augereau J, et al.
Org Biomol Chem . 2024 Dec; 23(3):734-743. PMID: 39623943
Dynamic covalent bonding (DCB) has been a rising concept for the past several years in materials sciences. This article describes how the bond lability involved in DCB is applied to...
2.
Filliatre M, Seren S, Embo-Ibouanga A, Joly J, Bouchaud V, Kelkoul I, et al.
ACS Omega . 2024 Sep; 9(37):39004-39012. PMID: 39310132
In search of better specificity and lower chances of resistance, protease-activatable alkoxyamine prodrugs to fight cancer have been proposed. These molecules are made of a peptide linked to an alkoxyamine....
3.
Embo-Ibouanga A, Nguyen M, Joly J, Coustets M, Augereau J, Paloque L, et al.
Pathogens . 2024 Jun; 13(6). PMID: 38921780
The expansion of drug resistant parasites sheds a serious concern on several neglected parasitic diseases. Our recent results on cancer led us to envision the use of peptide-alkoxyamines as a...
4.
Embo-Ibouanga A, Nguyen M, Paloque L, Coustets M, Joly J, Augereau J, et al.
Molecules . 2024 Mar; 29(6). PMID: 38543034
The emergence and spread of drug-resistant parasites shed a serious concern on the worldwide control of malaria, the most important tropical disease in terms of mortality and morbidity. This situation...
5.
Boudries D, Massot P, Parzy E, Seren S, Mellet P, Franconi J, et al.
J Magn Reson . 2023 Feb; 348:107383. PMID: 36724576
Development of very-low field MRI is an active area of research. It aims at reducing operating costs and improve portability. However, the signal-to-noise issue becomes prominent at ultra-low field (<1...
6.
Bouvet B, Sene S, Felix G, Havot J, Audran G, Marque S, et al.
Nanoscale . 2022 Nov; 15(1):144-153. PMID: 36326271
The design of smart nanoplatforms presenting well-definite structures able to achieve controlled cascade action remotely triggered by external stimuli presents a great challenge. We report here a new nanosystem consisting...
7.
Seren S, Joly J, Voisin P, Bouchaud V, Audran G, Marque S, et al.
J Med Chem . 2022 Jun; 65(13):9253-9266. PMID: 35764297
Current chemotherapies suffer low specificity and sometimes drug resistance. Neutrophil elastase activity in cancer is associated with poor prognosis and metastasis settlement. More generally, tumors harbor various and persistent protease...
8.
Audran G, Bagryanskaya E, Bagryanskaya I, Edeleva M, Joly J, Marque S, et al.
RSC Adv . 2022 May; 9(44):25776-25789. PMID: 35530086
Because the C-ON bond homolysis rate constant is an essential parameter of alkoxyamine reactivity, it is especially important to tune without a major alteration of the structure of the molecule....
9.
Larue L, Moussounda Moussounda Koumba T, Le Breton N, Vileno B, Arnoux P, Jouan-Hureaux V, et al.
ACS Appl Bio Mater . 2022 Jan; 4(2):1330-1339. PMID: 35014484
Photodynamic therapy (PDT) is a promising technique to treat different kinds of disease especially cancer. PDT requires three elements: molecular oxygen, a photoactivatable molecule called the photosensitizer (PS), and appropriate...
10.
Doni D, Meggiolaro M, Santos J, Audran G, Marque S, Costantini P, et al.
Biomedicines . 2021 Dec; 9(12). PMID: 34944579
Frataxin (FXN) is a highly conserved mitochondrial protein whose deficiency causes Friedreich's ataxia, a neurodegenerative disease. The precise physiological function of FXN is still unclear; however, there is experimental evidence...