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Georges St Laurent 3rd

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Articles 18
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11.
St Laurent 3rd G, Hammell N, McCaffrey T
Mech Ageing Dev . 2010 Mar; 131(5):299-305. PMID: 20346965
Advancing age remains the largest risk factor for devastating diseases, such as heart disease, stroke, and cancer. The mechanisms by which advancing age predisposes to disease are now beginning to...
12.
Gutierrez J, St Laurent 3rd G, Urcuqui-Inchima S
Theor Biol Med Model . 2010 Mar; 7:7. PMID: 20230643
Background: Signal transduction networks represent the information processing systems that dictate which dynamical regimes of biochemical activity can be accessible to a cell under certain circumstances. One of the major...
13.
St Laurent 3rd G, Savva Y, Reenan R
Neurosci Lett . 2009 Sep; 466(2):89-98. PMID: 19751800
The depth and complexity of the non-coding transcriptome in nervous system tissues provides a rich substrate for adenosine de-amination acting on RNA (ADAR). Non-coding RNAs (ncRNAs) serve diverse regulatory and...
14.
St Laurent 3rd G, Faghihi M, Wahlestedt C
Neurosci Lett . 2009 Aug; 466(2):81-8. PMID: 19699259
Non-protein-coding RNAs (ncRNAs) play critical roles on many levels of cellular information processing and pervasive expression of ncRNAs in the nervous system could help explain brain complexity. NcRNAs are enriched...
15.
Yang Z, Gagarin D, St Laurent 3rd G, Hammell N, Toma I, Hu C, et al.
Arterioscler Thromb Vasc Biol . 2009 May; 29(8):1213-9. PMID: 19443843
Objective: Increasing evidence suggests that chronic inflammation contributes to atherogenesis, and that acute inflammatory events cause plaque rupture, thrombosis, and myocardial infarction. The present studies examined how inflammatory factors, such...
16.
Faghihi M, Modarresi F, Khalil A, Wood D, Sahagan B, Morgan T, et al.
Nat Med . 2008 Jul; 14(7):723-30. PMID: 18587408
Recent efforts have revealed that numerous protein-coding messenger RNAs have natural antisense transcript partners, most of which seem to be noncoding RNAs. Here we identify a conserved noncoding antisense transcript...
17.
St Laurent 3rd G, Wahlestedt C
Trends Neurosci . 2007 Nov; 30(12):612-21. PMID: 17996312
The mammalian nervous system expresses numerous noncoding RNAs (ncRNAs). We propose that ncRNAs are capable of coupling the digital information universe of nucleic acids with the analog universe of cellular...
18.
Cahan P, Rovegno F, Mooney D, Newman J, St Laurent 3rd G, McCaffrey T
Gene . 2007 Jul; 401(1-2):12-8. PMID: 17651921
Microarray profiling of gene expression is a powerful tool for discovery, but the ability to manage and compare the resulting data can be problematic. Biological, experimental, and technical variations between...