George Thanassoulis
Overview
Explore the profile of George Thanassoulis including associated specialties, affiliations and a list of published articles.
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179
Citations
4496
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Recent Articles
1.
Bortnick A, Austin T, Hamerton E, Gudmundsdottir V, Emilsson V, Jennings L, et al.
J Am Heart Assoc
. 2025 Feb;
14(5):e036336.
PMID: 40008515
Background: Calcific aortic valve disease (CAVD), and ensuing severe aortic stenosis (AS), is the foremost valvular disorder of aging, yet preventive therapies are lacking. A better understanding of the molecular...
2.
Pencina K, Thanassoulis G, Pencina M, Toth P, Sniderman A
Cardiovasc Diabetol
. 2024 Dec;
23(1):448.
PMID: 39702291
Objectives: Whether "prediabetes" merits particular clinical attention beyond the management of associated risk factors is controversial, particularly given the expansion of the definition of prediabetes from HbA1c 6.0-6.4% to 5.7-6.4%....
3.
Anchouche K, Thanassoulis G
Curr Atheroscler Rep
. 2024 Nov;
27(1):7.
PMID: 39576403
Purpose Of Review: Elevated lipoprotein(a) (Lp[a]) is a genetically determined cardiovascular risk factor, causally linked to both atherosclerotic coronary artery disease and aortic stenosis. Elevated Lp(a) is widely prevalent, and...
4.
Bhatia H, Dweck M, Craig N, Capoulade R, Pibarot P, Trainor P, et al.
J Am Coll Cardiol
. 2024 Nov;
84(25):2430-2441.
PMID: 39545902
Background: Oxidized phospholipids (OxPLs) are carried by apolipoprotein B-100-containing lipoproteins (OxPL-apoB) including lipoprotein(a) (Lp[a]). Both OxPL-apoB and Lp(a) have been associated with calcific aortic valve disease (CAVD). Objectives: This study...
5.
Mancini G, Pearson G, Barry A, Couture P, Dayan N, Francis G, et al.
CJC Open
. 2024 Nov;
6(10):1189-1198.
PMID: 39525338
Background: In Canada, 2 guidelines provide guidance for the management of dyslipidemia. The Patients, Experience, Evidence, Research simplified lipid guidelines, intended for primary care practitioners, and the Canadian Cardiovascular Society...
6.
Trenkwalder T, Maj C, Al-Kassou B, Debiec R, Doppler S, Musameh M, et al.
JAMA Cardiol
. 2024 Nov;
10(2):145-154.
PMID: 39504041
Importance: Aortic stenosis (AS) and coronary artery disease (CAD) frequently coexist. However, it is unknown which genetic and cardiovascular risk factors might be AS-specific and which could be shared between...
7.
Soffer D, Marston N, Maki K, Jacobson T, Bittner V, Pena J, et al.
J Clin Lipidol
. 2024 Sep;
18(5):e647-e663.
PMID: 39256087
This National Lipid Association (NLA) Expert Clinical Consensus provides an overview of the physiologic and clinical considerations regarding the role of apolipoprotein B (apoB) measurement to guide clinical care based...
8.
Kohli-Lynch C, Thanassoulis G, Pencina M, Sehayek D, Pencina K, Moran A, et al.
JACC Adv
. 2024 Aug;
3(9):101090.
PMID: 39165836
No abstract available.
9.
Bilgic S, Pencina K, Pencina M, Cole J, Dufresne L, Thanassoulis G, et al.
Arterioscler Thromb Vasc Biol
. 2024 Aug;
44(10):2244-2251.
PMID: 39145394
Background: Recent observational and Mendelian randomization analyses have reported significant effects of VLDL-C (very-low density lipoprotein cholesterol) on risk that is independent of ApoB (apolipoprotein B). We aim to determine...
10.
What Guidelines Say About Risk Reduction: Major Data on the Link Between Lipid Lowering and Outcomes
Thanassoulis G, Welsh R, Hegele R
Can J Cardiol
. 2024 Aug;
40(8S):S13-S19.
PMID: 39111895
Atherosclerotic cardiovascular disease (ASCVD) is a significant health challenge, and apolipoprotein B (ApoB)-containing lipoproteins are increasingly recognized as central to its progression. Initially labelled as the "low-density lipoprotein hypothesis," our...