George Sigounas
Overview
Explore the profile of George Sigounas including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
17
Citations
1151
Followers
0
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Recent Articles
1.
George D, Bertrand F, Sigounas G
Adv Biol Regul
. 2024 Jan;
91:101013.
PMID: 38290285
Colon cancer is the second leading cause of cancer death. With over 153,000 new CRC cases predicted, it is the third most commonly diagnosed cancer. Early detection can lead to...
2.
Clark A, Bertrand F, Sigounas G
Adv Biol Regul
. 2023 Feb;
88:100957.
PMID: 36739740
Colorectal cancer (CRC) remains a challenging disease to treat due to several factors including stemness and epithelial to mesenchymal transition (EMT). Dysfunctional signaling pathways such as Notch and TGF-β contribute...
3.
Steinberg J, Azofeifa A, Sigounas G
Public Health Rep
. 2019 Aug;
134(5):456-460.
PMID: 31390301
No abstract available.
4.
Fauci A, Redfield R, Sigounas G, Weahkee M, Giroir B
JAMA
. 2019 Feb;
321(9):844-845.
PMID: 30730529
No abstract available.
5.
Vinson K, George D, Fender A, Bertrand F, Sigounas G
Int J Cancer
. 2015 Aug;
138(8):1835-42.
PMID: 26264352
Colorectal cancer (CRC) is the third leading cause of cancer death worldwide. It is also the third most common cancer diagnosis among men, and the second most common cancer diagnosis...
6.
Fender A, Nutter J, Fitzgerald T, Bertrand F, Sigounas G
J Cell Biochem
. 2015 Apr;
116(11):2517-27.
PMID: 25914224
Colorectal cancer (CRC) is the third leading cause of cancer death in the United States, resulting in an average of 50,000 deaths per year. Surgery and combination chemotherapy comprise current...
7.
Fitzgerald T, Rangan S, Dobbs L, Starr S, Sigounas G
J Surg Res
. 2014 Jun;
192(1):82-9.
PMID: 24953984
Background: Cancer stem cells may be associated with tumor progression and prognosis for colon cancer. We hypothesized that expression of Aldehyde dehydrogenase 1 (ALDH1) would increase with tumor progression and...
8.
Bertrand F, McCubrey J, Angus C, Nutter J, Sigounas G
Adv Biol Regul
. 2014 Jun;
56:51-65.
PMID: 24933481
Over the past decade, our understanding of the role that Notch-signaling has in tumorigenesis has shifted from leukemogenesis into cancers of solid tumors. Emerging data suggests that in addition to...
9.
Bertrand F, Angus C, Partis W, Sigounas G
Cell Cycle
. 2012 Oct;
11(23):4344-51.
PMID: 23032367
A hallmark of cancer is reactivation/alteration of pathways that control cellular differentiation during developmental processes. Evidence indicates that WNT, Notch, BMP and Hedgehog pathways have a role in normal epithelial...
10.
Lee N, Barber L, Akula S, Sigounas G, Kataria Y, Arce S
Clin Vaccine Immunol
. 2011 Jun;
18(8):1306-16.
PMID: 21653741
The presence of hypergammaglobulinemia, autoantibodies, and circulating immune complexes suggests that humoral immunity may contribute to the pathogenesis of sarcoidosis. However, little is known about the role played by B...