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George Newport

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Articles 10
Citations 912
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Recent Articles
1.
Newport G
Edinb Med Surg J . 2018 Oct; 77(191):349-385. PMID: 30331179
No abstract available.
2.
Newport G
Edinb Med Surg J . 2018 Oct; 78(192):1-47. PMID: 30331086
No abstract available.
3.
Murillo L, Newport G, Lan C, Habelitz S, Dungan J, Agabian N
Eukaryot Cell . 2005 Sep; 4(9):1562-73. PMID: 16151249
The ability to adhere to surfaces and develop as a multicellular community is an adaptation used by most microorganisms to survive in changing environments. Biofilm formation proceeds through distinct developmental...
4.
Braun B, van het Hoog M, dEnfert C, Martchenko M, Dungan J, Kuo A, et al.
PLoS Genet . 2005 Aug; 1(1):36-57. PMID: 16103911
Recent sequencing and assembly of the genome for the fungal pathogen Candida albicans used simple automated procedures for the identification of putative genes. We have reviewed the entire assembly, both...
5.
Hardt M, Thomas L, Dixon S, Newport G, Agabian N, Prakobphol A, et al.
Biochemistry . 2005 Feb; 44(8):2885-99. PMID: 15723531
Saliva plays many biological roles, from lubrication and digestion to regulating bacterial and leukocyte adhesion. To understand the functions of individual components and families of molecules, it is important to...
6.
Lan C, Rodarte G, Murillo L, Jones T, Davis R, Dungan J, et al.
Mol Microbiol . 2004 Sep; 53(5):1451-69. PMID: 15387822
Iron, an essential element for almost every organism, serves as a regulatory signal for the expression of virulence determinants in many prokaryotic and eukaryotic pathogens. Using a custom Affymetrix GeneChip...
7.
Bermudez-Cruz R, Ortega-Pierres G, Ceja V, Coral-Vazquez R, Fonseca R, Cervantes L, et al.
Arch Med Res . 2004 May; 35(3):199-208. PMID: 15163460
Background: It is well documented that Giardia duodenalis undergoes surface antigenic variation both in vivo and in vitro. Proteins involved have been characterized and referred to as VSP (variable surface...
8.
Jones T, Federspiel N, Chibana H, Dungan J, Kalman S, Magee B, et al.
Proc Natl Acad Sci U S A . 2004 May; 101(19):7329-34. PMID: 15123810
We present the diploid genome sequence of the fungal pathogen Candida albicans. Because C. albicans has no known haploid or homozygous form, sequencing was performed as a whole-genome shotgun of...
9.
Newport G, Kuo A, Flattery A, Gill C, Blake J, Kurtz M, et al.
J Biol Chem . 2002 Nov; 278(3):1713-20. PMID: 12419804
Deletion of the kexin gene (KEX2) in Candida albicans has a pleiotropic effect on phenotype and virulence due partly to a defect in the expression of two major virulence factors:...
10.
Lan C, Newport G, Murillo L, Jones T, Scherer S, Davis R, et al.
Proc Natl Acad Sci U S A . 2002 Oct; 99(23):14907-12. PMID: 12397174
Phase and antigenic variation are mechanisms used by microbial pathogens to stochastically change their cell surface composition. A related property, referred to as phenotypic switching, has been described for some...