George J Miller
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Explore the profile of George J Miller including associated specialties, affiliations and a list of published articles.
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53
Citations
1225
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Recent Articles
1.
Humphries S, Gable D, Cooper J, Ireland H, Stephens J, Hurel S, et al.
J Mol Med (Berl)
. 2007 Aug;
84(12):1005-14.
PMID: 17665514
Common variants of TCF7L2, encoding a beta-cell-expressed transcription factor, are strongly associated with increased risk of type 2 diabetes (T2D). We examined this association using both prospective and case-control designs....
2.
Muthumala A, Gable D, Palmen J, Cooper J, Stephens J, Miller G, et al.
Clin Sci (Lond)
. 2007 Jul;
113(12):467-72.
PMID: 17624939
There is strong evidence for the presence of a functional renin-angiotensin system in diabetogenic tissues, and ACE (angiotensin-converting enzyme) inhibitors may improve glucose metabolism in those individuals at high risk...
3.
Berry S, Miller G, Sanders T
Am J Clin Nutr
. 2007 Jun;
85(6):1486-94.
PMID: 17556683
Background: The process of randomization is used commercially to harden fats as an alternative to partial hydrogenation, but its effects on cardiovascular disease risk factors are uncertain. Objective: The objective...
4.
Thompson S, Sanders J, Stephens J, Miller G, Humphries S
Metabolism
. 2007 Apr;
56(5):662-9.
PMID: 17445542
The pleiotropic proinflammatory cytokine, interleukin 18, plays a role in innate immunity and, based on mouse models, influences obesity. We investigated variation within the IL18 gene and its effect on...
5.
Berry S, Woodward R, Yeoh C, Miller G, Sanders T
Lipids
. 2007 Apr;
42(4):315-23.
PMID: 17406926
The process of interesterification results in changes in triacylglycerol (TAG) structure and is used to increase the melting point of dietary fats. The acute health effects of this process on...
6.
Griffin M, Sanders T, Davies I, Morgan L, Millward D, Lewis F, et al.
Am J Clin Nutr
. 2006 Dec;
84(6):1290-8.
PMID: 17158408
Background: Insulin resistance is associated with elevated plasma triacylglycerol, low HDL concentrations, elevated postprandial lipemia, and a predominance of small, dense LDLs (sdLDLs). It has been hypothesized that the dietary...
7.
Humphries S, Cooper J, Talmud P, Miller G
Clin Chem
. 2006 Nov;
53(1):8-16.
PMID: 17130180
Background: One of the aims of cardiovascular genetics is to test the efficacy of the use of genetic information to predict cardiovascular risk. We therefore investigated whether inclusion of a...
8.
Vieira J, Whittall R, Cooper J, Miller G, Humphries S
Ann Hum Genet
. 2006 Oct;
70(Pt 6):697-704.
PMID: 17044844
Over 800 different missense mutations in the low density lipoprotein (LDL) receptor gene (LDLR) have been identified in patients with familial hypercholesterolaemia (FH). Only two of them, including the Alanine...
9.
Moore C, Bryant S, Mishra G, Krebs J, Browning L, Miller G, et al.
Nutrition
. 2006 Oct;
22(10):1012-24.
PMID: 17027436
Objective: Previous studies have demonstrated benefits of high-dose long-chain omega-3 polyunsaturated fatty acid (LC omega-3 PUFA) supplements on metabolic risk. Effects of increased dietary omega-3 PUFA, via oily fish and/or...
10.
Huth C, Heid I, Vollmert C, Gieger C, Grallert H, Wolford J, et al.
Diabetes
. 2006 Sep;
55(10):2915-21.
PMID: 17003362
Several lines of evidence indicate a causal role of the cytokine interleukin (IL)-6 in the development of type 2 diabetes in humans. Two common polymorphisms in the promoter of the...