George H Patterson
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Explore the profile of George H Patterson including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Jacoby-Morris K, Patterson G
Methods Mol Biol
. 2021 May;
2304:37-64.
PMID: 34028710
Fluorescence microscopy is advantageous for investigating biological processes and mechanisms in living cells. One of the most important considerations when designing an experiment is the selection of an appropriate fluorescent...
2.
Zhao H, Wu D, Nguyen A, Li Y, Adao R, Valkov E, et al.
iScience
. 2021 May;
24(6):102523.
PMID: 33997662
Nucleocapsid (N) protein of the SARS-CoV-2 virus packages the viral genome into well-defined ribonucleoprotein particles, but the molecular pathway is still unclear. N-protein is dimeric and consists of two folded...
3.
Shomron O, Nevo-Yassaf I, Aviad T, Yaffe Y, Zahavi E, Dukhovny A, et al.
J Cell Biol
. 2021 Apr;
220(6).
PMID: 33852719
COPII and COPI mediate the formation of membrane vesicles translocating in opposite directions within the secretory pathway. Live-cell and electron microscopy revealed a novel mode of function for COPII during...
4.
Zhao H, Wu D, Nguyen A, Li Y, Adao R, Valkov E, et al.
bioRxiv
. 2021 Feb;
PMID: 33594360
Nucleocapsid (N) protein of the SARS-CoV-2 virus packages the viral genome into well-defined ribonucleoprotein particles, but the molecular pathway is still unclear. N-protein is dimeric and consists of two folded...
5.
Lam N, Trinklein N, Buelow B, Patterson G, Ojha N, Kochenderfer J
Nat Commun
. 2020 Mar;
11(1):1319.
PMID: 32152289
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
6.
Lam N, Trinklein N, Buelow B, Patterson G, Ojha N, Kochenderfer J
Nat Commun
. 2020 Jan;
11(1):283.
PMID: 31941907
Chimeric antigen receptor (CAR)-expressing T cells targeting B-cell maturation antigen (BCMA) have activity against multiple myeloma, but improvements in anti-BCMA CARs are needed. We demonstrated recipient anti-CAR T-cell responses against...
7.
Ojha N, Rainey K, Patterson G
Nat Commun
. 2020 Jan;
11(1):21.
PMID: 31911590
Monitoring of protein oligomerization has benefited greatly from Förster Resonance Energy Transfer (FRET) measurements. Although donors and acceptors are typically fluorescent molecules with different spectra, homo-FRET can occur between fluorescent...
8.
Rainey K, Patterson G
Proc Natl Acad Sci U S A
. 2019 Jan;
116(3):864-873.
PMID: 30598438
FRET is a powerful approach to study the interactions of fluorescent molecules, and numerous methods have been developed to measure FRET in cells. Here, we present a method based on...
9.
Guo M, Chandris P, Giannini J, Trexler A, Fischer R, Chen J, et al.
Nat Methods
. 2018 May;
15(6):425-428.
PMID: 29735999
We combined instant structured illumination microscopy (iSIM) with total internal reflection fluorescence microscopy (TIRFM) in an approach referred to as instant TIRF-SIM, thereby improving the lateral spatial resolution of TIRFM...
10.
Salka K, Bhuvanendran S, Wilson K, Bozidis P, Mehta M, Rainey K, et al.
Sci Rep
. 2017 Feb;
7(1):16.
PMID: 28154412
Most nuclear-encoded mitochondrial proteins traffic from the cytosol to mitochondria. Some of these proteins localize at mitochondria-associated membranes (MAM), where mitochondria are closely apposed with the endoplasmic reticulum (ER). We...