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George H Gauss

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Articles 14
Citations 488
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Recent Articles
1.
Duan H, Lubner C, Tokmina-Lukaszewska M, Gauss G, Bothner B, King P, et al.
J Biol Chem . 2018 Feb; 293(13):4688-4701. PMID: 29462786
A newly recognized third fundamental mechanism of energy conservation in biology, electron bifurcation, uses free energy from exergonic redox reactions to drive endergonic redox reactions. Flavin-based electron bifurcation furnishes low-potential...
2.
Celis A, Gauss G, Streit B, Shisler K, Moraski G, Rodgers K, et al.
J Am Chem Soc . 2016 Dec; 139(5):1900-1911. PMID: 27936663
Coproheme decarboxylase catalyzes two sequential oxidative decarboxylations with HO as the oxidant, coproheme III as substrate and cofactor, and heme b as the product. Each reaction breaks a C-C bond...
3.
Prussia G, Gauss G, Mus F, Conner L, DuBois J, Peters J
FEBS Lett . 2016 Jul; 590(17):2991-6. PMID: 27447465
The characteristic His-Glu catalytic dyad of the disulfide oxidoreductase (DSOR) family of enzymes is replaced in 2-ketopropyl coenzyme M oxidoreductase/carboxylase (2-KPCC) by the residues Phe-His. 2-KPCC is the only known...
4.
Artz J, White S, Zadvornyy O, Fugate C, Hicks D, Gauss G, et al.
Front Bioeng Biotechnol . 2015 Jul; 3:97. PMID: 26217660
Mercuric ion reductase (MerA), a mercury detoxification enzyme, has been tuned by evolution to have high specificity for mercuric ions (Hg(2+)) and to catalyze their reduction to a more volatile,...
5.
Gauss G, Kleven M, Sendamarai A, Fleming M, Lawrence C
J Biol Chem . 2013 Jun; 288(28):20668-82. PMID: 23733181
Steap4 is a cell surface metalloreductase linked to obesity-associated insulin resistance. Initial characterization of its cell surface metalloreductase activity has been reported, but thorough biochemical characterization of this activity is...
6.
Gauss G, Reott M, Rocha E, Young M, Douglas T, Jeffrey Smith C, et al.
J Bacteriol . 2011 Oct; 194(1):15-27. PMID: 22020642
A factor contributing to the pathogenicity of Bacteroides fragilis, the most common anaerobic species isolated from clinical infections, is the bacterium's extreme aerotolerance, which allows survival in oxygenated tissues prior...
7.
Heinemann J, Maaty W, Gauss G, Akkaladevi N, Brumfield S, Rayaprolu V, et al.
Virology . 2011 Jul; 417(2):362-8. PMID: 21764098
One of the outstanding questions in biology today is the origin of viruses. We have discovered a protein in the hyperthermophile Sulfolobus solfataricus while following proteome regulation during viral infection...
8.
Jia H, Korolev S, Niedziela-Majka A, Maluf N, Gauss G, Myong S, et al.
J Mol Biol . 2011 Jun; 411(3):633-48. PMID: 21704638
Escherichia coli UvrD is a superfamily 1 DNA helicase and single-stranded DNA (ssDNA) translocase that functions in DNA repair and plasmid replication and as an anti-recombinase by removing RecA protein...
9.
Gauss G, Benas P, Wiedenheft B, Young M, Douglas T, Lawrence C
Biochemistry . 2006 Sep; 45(36):10815-27. PMID: 16953567
The superfamily of ferritin-like proteins has recently expanded to include a phylogenetically distinct class of proteins termed DPS-like (DPSL) proteins. Despite their distinct genetic signatures, members of this subclass share...
10.
Ramsay B, Wiedenheft B, Allen M, Gauss G, Lawrence C, Young M, et al.
J Inorg Biochem . 2006 Jan; 100(5-6):1061-8. PMID: 16412514
Oxidative stress is a universal phenomenon experienced by organisms in all domains of life. Proteins like those in the ferritin-like di-iron carboxylate superfamily have evolved to manage this stress. Here...