Blake Wiedenheft
Overview
Explore the profile of Blake Wiedenheft including associated specialties, affiliations and a list of published articles.
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Articles
89
Citations
5297
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Recent Articles
1.
Buyukyoruk M, Krishna P, Santiago-Frangos A, Wiedenheft B
CRISPR J
. 2025 Jan;
PMID: 39792480
Bacteria and archaea acquire resistance to genetic parasites by preferentially integrating short fragments of foreign DNA at one end of a Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR). "Leader" DNA...
2.
Schwartz M, Dunn S, Gendron W, Helm J, Kamau W, Mark-Shadbolt M, et al.
Trends Ecol Evol
. 2024 Dec;
40(3):296-307.
PMID: 39667987
Introducing new genes and new species into ecosystems where they have not previously existed presents opportunities and complex, multivalue decisions for conservation biologists and the public. Both synthetic biology and...
3.
Burman N, Belukhina S, Depardieu F, Wilkinson R, Skutel M, Santiago-Frangos A, et al.
Nature
. 2024 Dec;
636(8043):E8.
PMID: 39633059
No abstract available.
4.
Burman N, Belukhina S, Depardieu F, Wilkinson R, Skutel M, Santiago-Frangos A, et al.
Nature
. 2024 Aug;
634(8033):424-431.
PMID: 39111359
Viruses compete with each other for limited cellular resources, and some deliver defence mechanisms that protect the host from competing genetic parasites. The phage antirestriction induced system (PARIS) is a...
5.
Wood T, Henriques W, Cullen H, Romero M, Blengini C, Sarathy S, et al.
Res Sq
. 2024 Jul;
PMID: 39041030
The human genome contains 24 -like capsid genes derived from deactivated retrotransposons conserved among eutherians. Although some of their encoded proteins retain the ability to form capsids and even transfer...
6.
Snyder L, Kilde I, Nemudryi A, Wiedenheft B, Koutmos M, Koutmou K
RNA
. 2024 Jun;
30(9):1141-1150.
PMID: 38942480
SARS-CoV-2, the causative virus of the COVID-19 pandemic, follows SARS and MERS as recent zoonotic coronaviruses causing severe respiratory illness and death in humans. The recurrent impact of zoonotic coronaviruses...
7.
Wood T, Henriques W, Cullen H, Romero M, Blengini C, Sarathy S, et al.
bioRxiv
. 2024 May;
PMID: 38798495
The human genome contains 24 -like capsid genes derived from deactivated retrotransposons conserved among eutherians. Although some of their encoded proteins retain the ability to form capsids and even transfer...
8.
Nemudraia A, Nemudryi A, Wiedenheft B
Science
. 2024 Apr;
384(6697):808-814.
PMID: 38662916
Genome editing with CRISPR RNA-guided endonucleases generates DNA breaks that are resolved by cellular DNA repair machinery. However, analogous methods to manipulate RNA remain unavailable. We show that site-specific RNA...
9.
Henriques W, Young J, Nemudryi A, Nemudraia A, Wiedenheft B, Malik H
Mol Biol Evol
. 2024 Mar;
41(4).
PMID: 38507667
Selfish genetic elements comprise significant fractions of mammalian genomes. In rare instances, host genomes domesticate segments of these elements for function. Using a complete human genome assembly and 25 additional...
10.
Burman N, Belukhina S, Depardieu F, Wilkinson R, Skutel M, Santiago-Frangos A, et al.
bioRxiv
. 2024 Jan;
PMID: 38260645
Viruses compete with each other for limited cellular resources, and some viruses deliver defense mechanisms that protect the host from competing genetic parasites. PARIS is a defense system, often encoded...