George Giambasu
Overview
Explore the profile of George Giambasu including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
43
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0
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Recent Articles
1.
Rosenblum S, Soueid D, Giambasu G, Vander Roest S, Pasternak A, DiMauro E, et al.
RSC Med Chem
. 2024 May;
15(5):1539-1546.
PMID: 38784453
Dysregulation of the networking of RNA-binding proteins (RBPs) and RNAs drives many human diseases, including cancers, and the targeting of RNA-protein interactions (RPIs) has emerged as an exciting area of...
2.
Sengupta R, van Schie S, Giambasu G, Dai Q, Yesselman J, York D, et al.
RNA
. 2015 Nov;
22(1):32-48.
PMID: 26567314
Biological catalysis hinges on the precise structural integrity of an active site that binds and transforms its substrates and meeting this requirement presents a unique challenge for RNA enzymes. Functional...
3.
Heldenbrand H, Janowski P, Giambasu G, Giese T, Wedekind J, York D
J Am Chem Soc
. 2014 May;
136(22):7789-92.
PMID: 24842535
The hairpin ribozyme accelerates a phosphoryl transfer reaction without catalytic participation of divalent metal ions. Residues A38 and G8 have been implicated as playing roles in general acid and base...
4.
Lee T, Giambasu G, Harris M, York D
J Phys Chem Lett
. 2011 Dec;
2(20):2538-2543.
PMID: 22200005
The structure and dynamics of the hepatitis delta virus ribozyme (HDVr) are studies using molecular dynamics simulations at several stages along its catalytic reaction path, including reactant, activated precursor, transition...